Available Open Access under CC-BY-NC licence. Health literacy addresses a range of social dimensions of health, including knowledge, navigation and communication, as well as individual and organizational skills for accessing, understanding, evaluating and using information. Particularly over the past decade, health literacy has globally become a major public health concern as an asset for promoting health, wellbeing and sustainable development.
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Blanco tequila’s journey—from mature agave and skilled harvesting to slow cooking, fermentation, and distillation—creates a pure, vibrant spirit that reflects true craftsmanship and tradition.
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Matrix metalloproteinases (MMPs) are members of an enzyme family and are critical for maintaining tissue allostasis. MMPs can catalyze normal turnover of the extracellular matrix (ECM) together with other metalloproteinases such as ADAM (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) families. MMP activity is also regulated by a group of endogenous proteins called tissue inhibitor of metalloproteinases (TIMPs). All these proteins have a pivotal role involving ECM remodelling in normal physiological processes such as wound healing, embryogenesis, angiogenesis, bone remodelling, immunity, and the female reproductive cycle. An imbalance in the expression or activity of MMPs can also have important consequences in diseases such as cancer, cardiovascular disease, peripheral vascular disease, chronic leg ulcers, and multiple sclerosis. In recent years, MMPs have been found to play an important role in the field of precision medicine, as they may serve as biomarkers that may predict an individual’s disease predisposition, state, or progression. MMPs are also thought to be a sensible target for molecular therapy. The aim of this Special Issue is to explore the most recent findings in this field that may have an impact in healthcare systems.
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Explore whether plain ceilings are truly enough! Discover 10 creative ceiling design ideas—from wooden panels to fibre optic lighting—that instantly elevate your home interiors. Perfect for modern living rooms, bedrooms, and dining areas looking for a stylish upgrade. https://boosty.to/interiordesignervarun/posts/8db7bdc3-e190-4440-a5c6-76df37015c9f
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This open access book explores commentaries on an influential text of pre-Copernican astronomy in Europe. It features essays that take a close look at key intellectuals and how they engaged with the main ideas of this qualitative introduction to geocentric cosmology. Johannes de Sacrobosco compiled his Tractatus de sphaera during the thirteenth century in the frame of his teaching activities at the then recently founded University of Paris. It soon became a mandatory text all over Europe. As a result, a tradition of commentaries to the text was soon established and flourished until the second half of the 17th century. Here, readers will find an informative overview of these commentaries complete with a rich context. The essays explore the educational and social backgrounds of the writers. They also detail how their careers developed after the publication of their commentaries, the institutions and patrons they were affiliated with, what their agenda was, and whether and how they actually accomplished it. The editor of this collection considers these scientific commentaries as genuine scientific works. The contributors investigate them here not only in reference to the work on which it comments but also, and especially, as independent scientific contributions that are socially, institutionally, and intellectually contextualized around their authors.
In England in Europe, Elizabeth Tyler focuses on two histories: the Encomium Emmae Reginae, written for Emma the wife of the Æthelred II and Cnut, and The Life of King Edward, written for Edith the wife of Edward the Confessor.Tyler offers a bold literary and historical analysis of both texts and reveals how the two queens actively engaged in the patronage of history-writing and poetry to exercise their royal authority. Tyler’s innovative combination of attention to intertextuality and regard for social networks emphasizes the role of women at the centre of Anglo-Saxon and Anglo-Norman court literature. In doing so, she argues that both Emma and Edith’s negotiation of conquests and factionalism created powerful models of queenly patronage that were subsequently adopted by individuals such as Queen Margaret of Scotland, Countess Adela of Blois, Queen Edith/Matilda, and Queen Adeliza.
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