Ronald Reagan

PD-US

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Anjali Hanrao

Frank Norris

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This short 1899 romance was based on Norris's courtship of his wife. It features a San Francisco journalist, Condy Rivers, who falls in love with the daughter of a wealthy family that believes him to be very much beneath her. Willa Cather praised the novel as all wheat and no chaff.

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The break on immune tolerance is a common point between autoimmune diseases and the uncontrolled effector immune responses against allo-antigens in transplantation. Among the past years, several approaches to restore a suppressive immune state have included the targeting of co-stimulatory/inhibitory molecules on immune cells, the promotion or blockade of pivotal cytokines, and the extensive study on how to isolate and expand suppressive cells with the purpose to re-infuse them in patients. To date, the availability of new technologies has permitted to learn, in a more detailed way, the immune mechanisms carried out by suppressive lymphocytes, together with the identification of new potential candidates to target in our quest for immune tolerance. For example, the attractive concepts of lymphocyte plasticity and function stability, supported by the finding of new transcription factors, have opened a new window in the understanding of T cell differentiation, effector cell commitment and immune regulatory function. On the other hand, the discovery of new members of the Ig superfamily ligand, VISTA; the intriguing role of modulatory molecules like Retinoic Acid, Neuropilin-1, Fc gamma receptors, or cytokines such as IL-33, among others, are revealing new possibilities in the development of new strategies to conquer our obsession: immune tolerance. Here, we gather the latest information regarding new targets and cellular processes, including an update on current cellular therapies and the exciting coming approaches to cure autoimmunity and permit transplant acceptance.

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A Section 508 audit helps you confirm accessibility standards of your website. Section 508 VPAT requirements should be your priority before procurement teams ask for proof. So keep reading to find out what are Section 508 compliance requirements and how to audit your product.

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Discover why payroll automation is becoming essential for small businesses in 2025. This article highlights how the Best payroll solutions for small businesses improve accuracy, boost compliance, and save hours of manual work. Learn how cloud-based systems, automated reports, secure data handling, and HR integration help businesses simplify operations. Explore why adopting the right payroll software is a strategic decision for growth and financial stability.

Henri Poincaré

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Gilbert Parker

PD-US

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Die beschäftigungspolitischen Wirkungen einer Arbeitszeitverkürzung sind in der Fachliteratur intensiv diskutiert worden. Allerdings bleibt die theoretische Frage offen, ob eine Arbeitszeitverkürzung eine Steigerung der mit positiven Externalitäten verbundenen Frauenerwerbsbeteiligung mit sich bringen würde. Empirische Befunde deuten darauf hin. Die Gestaltung eines theoretischen Analyserahmens, der die Modellierung der Arbeitszeit als Determinante der Erwerbsbeteiligung und die Berücksichtigung aller Nebeneffekte ermöglichte, setzte unter anderem die Definition eines neuen Erwerbsbeteiligungskriteriums voraus. Bei plausiblen Annahmen über die Arbeitszeitpräferenzen konnte gezeigt werden, daß eine Verkürzung der Tagesarbeitszeit die Erwerbsbeteiligung erhöhen kann. Dabei sind das Lohnniveau und die Kosten der Kinderbetreuung ausschlaggebend.

P. Martin (Peter Martin) Duncan

PD-US

PD-US

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There is at present no publication specifically dedicated to analyzing the philosophical implications of augmented reality. Applications cover diverse fields like psychopathology and education, implications concern issues as diverse as negative knowledge, group cognition, the internet of things, and ontological issues, among others. In this way, it is intended not only to generate answers, but also, to draw attention to new problems that arise with the diffusion of augmented reality. In order to contemplate these problems from diverse perspectives, the authors are from a variety of fields - philosophy, computer sciences, education, psychology, and many more. Accordingly, the volume offers varied and interesting contributions which are of interest to professionals from multiple disciplines.

W. M Maskell

PD-US

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Many of the sections included in the technical delivery conditions can only be used s by an acceptance for individual cases due to the limited application range of rectangular hollow section joints. The presented design approach allows for the design of K joints with thin-walled chord sections and makes these sections accessible to design. Additionally, it enables the design of joints with small gaps.

Herbert George Jenkins

PD-US

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This open access collection of essays examines the literary advice industry since its emergence in Anglo-American literary culture in the mid-nineteenth century within the context of the professionalization of the literary field and the continued debate on creative writing as art and craft. Often dismissed as commercial and stereotypical by authors and specialists alike, literary advice has nonetheless remained a flourishing business, embodying the unquestioned values of a literary system, but also functioning as a sign of a literary system in transition. Exploring the rise of new online amateur writing cultures in the twenty-first century, this collection of essays considers how literary advice proliferates globally, leading to new forms and genres.

Learn how timely gum treatment protects your oral health and why choosing the top dentist in locality matters.

seosoft

Walter Scott

PD-US

Nareshkumar

Shankar Distillers

Straight Bourbon Whiskey represents an enduring American tradition, shaped by historic distillation methods and strict regulations that preserve its identity. Crafted with corn-rich mash bills and aged in new charred oak, its complexity deepens through climatic interaction with wood. Today’s distillers blend heritage with innovation to create premium expressions that appeal worldwide.

Guy de Maupassant

PD-US

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« Un homme n’aurait pas idée d’écrire un livre sur la situation singulière qu’occupent dans l’humanité les mâles », affirmait en 1949 la philosophe française Simone de Beauvoir. Les profondes mutations qui ont affecté le genre et la sexualité ces dernières décennies ont pourtant fait mentir l’auteure du Deuxième sexe : le masculin est désormais objet de multiples débats, réflexions et recherches. Rassemblés dans une perspective de décloisonnement disciplinaire, des historiens, sociologues, philosophes, anthropologues et spécialistes de la littérature ou du cinéma mettent ici en évidence le caractère pluriel des expériences et idéologies de la virilité. Ils montrent également que la construction du masculin ne s’opère jamais en vase clos, mais bien en étroite corrélation avec celle du féminin. Ce sont donc au final les deux « sexes » qui sont au cœur de ce volume qui, en dénaturalisant les catégories sociales, éclaire le caractère contingent, quotidiennement ré-inventé de ce qui apparaît évident : être une femme ou un homme.

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Social perspective defines the human skill of changing between the point of view of oneself and the other. It takes meta-perspectives and applies them to the different (suspected) point of views. If one knows how the interaction-partner sees the world, one can assume the partner´s willingness to act and consider it for one´s own plan of action.

PD-US

Listed in magazine table of contents as "Blackout."