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Antimicrobial resistance (AMR) is a global problem with extremely complex epidemiology involving the direct and indirect transmission of antibiotic resistant pathogens and mobile genetic elements between humans, animals, and the environment. AMR is, therefore, recognized as a ‘One Health’ issue. Data that describe AMR prevalence and trends are required to enable the judicious and prudent use of antimicrobials in animals, which has implications both from veterinary and animal welfare aspects as well as from a zoonotic and public health perspective. Horses are a potential reservoir of AMR for humans due to close human–animal contact, as was demonstrated with shared human and horse methicillin-resistant Staphylococcus aureus (MRSA) strains causing outbreaks in equine hospitals. Extended-spectrum beta-lactamase-producing Enterobacteriaceae, considered as clinically and economically important to the AMR burden in human and veterinary medicine, has been reported in both community and clinic equine populations. Strains of Enterobacteriaceae pose a major worldwide threat due to the geographical expansion of ESBL-producing clones as well as the horizontal interspecies dissemination of ESBL-encoding plasmids and genes. In human medicine, ESBL-E infection is associated with increased morbidity, mortality, length of hospital stay, delay of targeted appropriate treatment, and higher costs. These issues also need to be addressed in horses. This Special Issue on AMR in horses encompasses several papers that describe the prevalence, risk factors, and molecular data on MDR bacteria in healthy horses in Canada, Japan, Spain, and Israel, in addition to papers that describe the clinical impact of MDR bacteria in diseased horses in Austria, USA, France and Israel.
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Fictional reconstructions of the Gospels continue to find a place in contemporary literature and in the popular imagination. Present day writers of New Testament fiction and drama are usually considered as part of a tradition formed by mid-to-late-twentieth-century authors such as Robert Graves, Nikos Kazantzakis and Anthony Burgess. This book looks back further to the late-nineteenth and early-twentieth centuries, when the templates of the majority of today’s Gospel fictions and dramas were set down. In doing so, it examines the extent to which significant works of biblical scholarship both influenced and inspired literary works. Focusing on writers such as Oscar Wilde, George Moore and Marie Corelli, this timely new addition to the English Association Monographs series will be essential reading for scholars working at the intersection of literature and theology.
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A mysterious attack on Margaret Trelawny's father brings young lawyer Malcolm Ross into the eminent Egyptologist's home; amid mummies and Oriental relics, ancient forces greater than they previously could have imagined are stirring. The Egyptian Queen Tera has been awakened, and is coming to take what she believes to be hers - whatever the cost to the Trelawny family. Set in London, Cornwall and Egypt, and written at a time when a fascination with the East pervaded Edwardian England, The Jewel of Seven Stars reflected the interest both in the Orient's perceived savagery and moral degradation, and in its exotic beauty and opulence. Kate Hebblethwaite's introduction explores the politics and history behind The Jewel of Seven Stars, and looks at the gender issues within late Victorian and Edwardian stories of the supernatural. This edition also contains a chronology and further reading.