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Nerve sheath tumors can be a significant cause of morbidity for many patients. These include benign tumors such as schwannomas, diffuse and plexiform neurofibromas, and atypical neurofibromas, as well as the aggressive soft tissue sarcoma known as the malignant peripheral nerve sheath tumor (MPNST). Nerve sheath tumors occur sporadically and in the context of the clinical neuro-genetic tumor predisposition syndromes neurofibromatosis type 1 (NF1) and type 2 (NF2). Historically, the mainstay of treatment for nerve sheath tumors has been surgery. However, for both benign and malignant nerve sheath tumors, there is a high recurrence rate, highlighting the pressing need for novel therapies. As we have entered the genomic era, the hope is that an improved understanding of the genetics, and therefore the biology, of these tumors will ultimately lead to therapies that result in better outcomes. In this Special Issue, we include both review articles and original research related to the genomic understanding and modeling of schwannomas, plexiform and diffuse neurofibromas, atypical neurofibromas, and malignant peripheral nerve sheath tumors as well as genomic methods being developed and applied to advance our understanding of these tumors.

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Social perspective defines the human skill of changing between the point of view of oneself and the other. It takes meta-perspectives and applies them to the different (suspected) point of views. If one knows how the interaction-partner sees the world, one can assume the partner´s willingness to act and consider it for one´s own plan of action.

Frank Richard Stockton

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Edward Hoare

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The shift from hand-written to printed books left its mark on narrative literature in Western Europe. The essays in this volume address developments in the history of early printed narrative texts as well as publication strategies in a number of vernacular languages. Topics covered include the selection of texts that made it into print, stages in their printed history, textual adaptations, the use of woodcuts and the development of title pages.

me

yurr

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"Beyond musical works: new perspectives on music ontology and performance
What are musical works? How are they constructed in our minds? Which material things allow us to speak about them in the first place? Does a specific way of conceiving musical works limit their performative potentials? Which alternative, more productive images of musical work can be devised?

Virtual Works – Actual Things addresses contemporary music ontological discourses, challenging dominant musicological accounts, questioning their authoritative foundation and moving towards dynamic perspectives devised by music practitioners and artist researchers. Specific attention is given to the relationship between the virtual multiplicities that enable the construction of an image of a musical work and the actual, concrete materials that make such a construction possible. With contributions by prominent scholars, this book is a wide-ranging and fascinating collection of essays, which will be of great interest for artistic research, contemporary musicology, music philosophy, performance studies and music pedagogy alike.

Contributors: David Davies (McGill University, Montreal), Andreas Dorschel (University of the Arts Graz), Lydia Goehr (Columbia University, New York), Kathy Kiloh (OCAD University, Toronto), Jake McNulty (Columbia University, New York), Gunnar Hindrichs (University of Basel), John Rink (University of Cambridge)"

John Marshall

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The open access journal Micromachines invites manuscript submissions for the Special Issue “Silicon Photonics Bloom”. The past two decades have witnessed a tremendous growth of silicon photonics. Lab-scale research on simple passive component designs is now being expanded by on-chip hybrid systems architectures. With the recent injection of government and private funding, we are living the 1980s of the electronic industry, when the first merchant foundries were established. Soon, we will see more and more merchant foundries proposing well-established electronic design tools, product development kits, and mature component libraries. The open access journal Micromachines invites the submission of manuscripts in the developing area of silicon photonics. The goal of this Special Issue is to highlight the recent developments in this cutting-edge technology.]

Samuel Richardson

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For a fascinating glimpse into eighteenth-century morals and values, take a look at Samuel Richardson's Pamela, or Virtue Rewarded. A blockbuster of a bestseller in its day, Pamela recounts the tribulations of a poor housekeeper who is forced constantly to fend off the prurient advances of her employer. Her reward? Pamela is offered -- and accepts -- her lustful master's hand in marriage and is thrust into upper-class society.

Charles P. (Charles Palfray) Bosson

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Ellen Thorneycroft Fowler

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Hugh Williams (editor)

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John MacLean

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Jeetendra Tarate

Girl Scouts of the United States of America

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Der Asiatisch-Pazifischen Wirtschaftskooperation (APEC) gehört der überwiegende Teil der Pazifikanrainerstaaten an. Darunter die ostasiatischen Tigerländer, Japan, die ASEAN-Staaten, die NAFTA-Staaten, Australien und Neuseeland. Die Teilnehmer der APEC haben sich zum Ziel gesetzt, bis zum Jahr 2020 freien Handel und freie Investitionen innerhalb der APEC-Region zu erreichen. Vor dem Hintergrund der aktuellen Regionalisierungsdebatte wird untersucht, unter welchen Voraussetzungen dieses Vorhaben verwirklicht werden soll, welche Schwierigkeiten bestehen und welche Wirkungen resultieren können.

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Anpassung an den Klimawandel; Gesellschaft und Klimawandel; Klimafolgen; Klimaschutz; Klimawandel in Norddeutschland; Regionales Klimaassessment

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The main points of reflection posed by the volume concern the identity and role of the teachers in the digital society: teacher training, educational planning and the praxic effects of new media. The text proposes reflections on current issues, such as assessment - intended as a training process of knowledge acquisition - and innovative applications of academic research to new learning needs. The purpose of this contribution is to link constructs and paradigms to identify what makes a teacher highly qualified, from an eminently pedagogical point of view.

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The Internet and the proceeding digitalisation of content - such as music, videos and written texts - have led to profound and complex challenges in the field of Copyright Law, especially with regard to questions of enforcement as well as adequate compensation of right holders. In recent years, several alternative compensation schemes have been proposed, seeking to solve these issues. In Germany, the discussion still focuses on the so-called "cultural flatrate", that is, in a nutshell, a limitation to copyrights which would legalize sharing of content online. Every holder of a broadband connection to the Internet would have to pay a monthly fee which would be used to remunerate the right holders.This advisory opinion was compiled on behalf of the parliamentary group of the German political party "Bündnis 90/DIE GRÜNEN". The author comprehensively analyses the feasibility of the described alternative compensation scheme under German and European law, discussing both legal and economic obstacles and possible impacts based on a variety of different economic prerequisites.In diesem von der Bundestagsfraktion Bündnis 90/Die Grünen in Auftrag gegebenem ergebnisoffenem Gutachten untersucht Prof. Spindler die rechtliche und ökonomische Umsetzbarkeit sowie Ausgestaltung eines Ansatzes zur sog. „Kulturflatrate“. Die Fragestellung war, ob ein Pauschalvergütungsansatz auf Breitbandanschlüsse ein Baustein für ein gerechteres, modernes Urheberrecht, für angemessene Vergütung für die UrheberInnen und einen gesellschaftlichen Interessensausgleich sein kann. Das umfassende und detailreiche Gutachten leistet einen wesentlichen Beitrag zur Diskussion um die Zukunft des Urheberrechts, die in Zeiten des globalen Internets in praktisch jedem Land geführt wird. Es wird vollumfänglich der Öffentlichkeit zugänglich gemacht, damit die Ergebnisse von allen Interessierten genutzt und weiterentwickelt werden können. Prof. Spindler zeigt in seinem Gutachten auf, dass ein Pauschalvergütungsansatz verfassungsrechtlich zulässig und ein attraktives Modell zur angemessenen Vergütung für Kreative sein kann. Für die Situation der NutzerInnen bietet er eine geeignete Alternative zu repressiven und gesellschaftlich höchst konfliktträchtigen Formen der Rechtsdurchsetzung. Gleichzeitig wird aber auch auf gewichtige Schwierigkeiten und Hürden bei der Umsetzung eines solchen Modells hingewiesen. Das Gutachten und dieser Text erschienen zunächst unter der Creative Commons Lizenz BY-NC-ND auf der Internetpräsenz der Bundestagsfraktion von Bündnis 90/ Die Grünen. Diese Überarbeitung hat den Stand 08. Januar 2014.

Annika Sandén (editor)

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Today's society is often characterized as a knowledge society, in contrast to the earlier industrial society. Historians however know that all societies are and have been knowledge societies. Without the ability to create, transfer, and use knowledge, between individuals and groups, power areas would neither have been built nor maintained. This edited volume reflects how historical actors, both those in power as well as laymen and officials, have produced and utilised information and knowledge from the Middle Ages until today. It acommodates research into census, urbanisation, history of kings and queens, exercise of public authority, social and political movements, disciplining and formation of opinion. In Kunskapens tider. Historiska perspektiv p kunskapssamhllet (The knowledge society. A historical perspective) nine researchers from the Department of History at Stockholm University contribute with examples of the need for and use of knowledge, in different historical situations and periods. *** This book is in Swedish: Dagens samhlle karaktriseras ofta som kunskapssamhllet, till skillnad frn det tidigare industrisamhllet. Historiker vet dock att alla samhllen r och har varit kunskapssamhllen: Utan mjligheter att skapa, verfra och anvnda kunskap, svl individer som grupper emellan, hade maktomrden varken kunnat byggas eller vidmakthllas. Antologin speglar hur historiska aktrer, svl makthavare som lekmn och tjnstemn, har producerat och utnyttjat information och kunskap frn medeltiden till idag. Hr ryms forskning om folkrkning, urbanisering, kungars historieskrivning, myndighetsutvning, sociala och politiska rrelser, disciplinering och opinionsbildning. I Kunskapens tider bidrar nio medarbetare frn Historiska institutionen vid Stockholms universitet med exempel p hur behovet och anvndandet av kunskap sett ut i olika historiska situationer och tidsperioder.

Hammad