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Design thinking has emerged as a powerful problem-solving framework that prioritizes empathy, innovation, and human-centered solutions.
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Autophagy (also known as macroautophagy) is an evolutionarily conserved process by which cytoplasmic components are nonselectively enclosed within a double-membrane vesicle known as the autophagosome and delivered to the vacuole for degradation of toxic components and recycling of needed nutrients. This catabolic process is required for the adequate adaptation and response of the cell, and correspondingly the whole organism, to different types of stress including nutrient starvation or oxidative damage. Autophagy has been extensively investigated in yeasts and mammals but the identification of autophagy-related (ATG) genes in plant and algal genomes together with the characterization of autophagy-deficient mutants in plants have revealed that this process is structurally and functionally conserved in photosynthetic eukaryotes. Recent studies have demonstrated that autophagy is active at a basal level under normal growth in plants and is upregulated during senescence and in response to nutrient limitation, oxidative stress, salt and drought conditions and pathogen attack. Autophagy was initially considered as a non-selective pathway, but numerous observations mainly obtained in yeasts revealed that autophagy can also selectively eliminate specific proteins, protein complexes and organelles. Interestingly, several types of selective autophagy appear to be also conserved in plants, and the degradation of protein aggregates through specific adaptors or the delivery of chloroplast material to the vacuole via autophagy has been reported. This research topic aims to gather recent progress on different aspects of autophagy in plants and algae. We welcome all types of articles including original research, methods, opinions and reviews that provide new insights about the autophagy process and its regulation.
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Single Molecule Magnets (SMMs) showing bistability and quantum phenomena are promising candidates for spintronic applications. In recent years, the study of hybrid surfaces composed of SMMs on conductive and magnetic surfaces has attracted increasing interest. In this work the preparation of hybrid surfaces made by terbium bis(phthalocyaninato) and Fe4 SMMs is reported. The surfaces were structurally and magnetically characterized by means of laboratory and large scale facility techniques. This investigation has provided interesting hints towards their application in spintronic devices and has paved the way for the magnetic characterization of Fe4 at the single molecule level.
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Detailed analyses of poverty and wellbeing in developing countries, based on household surveys, have been ongoing for more than three decades. The large majority of developing countries now regularly conduct a variety of household surveys, and their information base with respect to poverty and wellbeing has improved dramatically. Nevertheless, appropriate measurement of poverty remains complex and controversial. This is particularly true in developing countries where (i) the stakes with respect to poverty reduction are high; (ii) the determinants of living standards are often volatile; and (iii) related information bases, while much improved, are often characterized by significant non-sample error. It also remains, to a surprisingly high degree, an activity undertaken by technical assistance personnel and consultants based in developed countries. This book seeks to enhance the transparency, replicability, and comparability of existing practice. It also aims to significantly lower the barriers to entry to the conduct of rigorous poverty measurement and increase the participation of analysts from developing countries in their own poverty assessments. The book focuses on two domains: the measurement of absolute consumption poverty and a first-order dominance approach to multidimensional welfare analysis. In each domain, it provides a series of computer codes designed to facilitate analysis by allowing the analyst to start from a flexible and known base. The volume covers the theoretical grounding for the code streams provided, a chapter on ‘estimation in practice’, a series of eleven case studies where the code streams are operationalized, a synthesis, an extension to inequality, and a look forward.
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This volume widens the scope of research into the relation between religion and Enlightenment. The contributions demonstrate the impact of changing worldviews in a variety of intellectual disciplines and cultural milieus. Readership: Cultural historians, historians of ideas, of philosophy, and of religion, interested in the debate over the place of religion in the late seventeenth and early eighteenth century Dutch Republic. Keywords: controversy literature, epistolary culture, early modern knowledge cultures, Enlightenment encyclopedias, intellectual history, pietism, political theory, Romeijn de Hooghe, theology
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