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This book presents recent research results related to various applications of computer vision methods in the widely understood contexts of automation and robotics. As the current progress of image analysis applications may be easily observed in various areas of everyday life, it becomes one of the most essential elements of development of Industry 4.0 solutions. Some of the examples, partially discussed in individual chapters, may be related to the visual navigation of mobile robots and drones, monitoring of industrial production lines, non-destructive evaluation and testing, monitoring of the IoT devices or the 3D printing process and the quality assessment of manufactured objects, video surveillance systems, and decision support in autonomous vehicles.

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The Global Metaverse in Healthcare Market is projected to grow at a CAGR of around 32% during the forecast period, i.e., 2023-28. Read More: https://www.marknteladvisors.com/research-library/metaverse-healthcare-market.html

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Aims and Scope: The Research Topic is designed to feature the latest innovative and leading-edge research, reviews and opinions on the study of complex and dynamic processes related to the mammalian immune system and cancer. All papers were meticulously selected to present our readers the multidisciplinary approach to tackle the existing challenges faced in these important fields. From high throughput experimental methodologies to computational and theoretical approaches, the articles are intended to introduce physicists, chemists, computer scientists, biologists and immunologists the idea of systems biology approach to the understanding of mammalian immune system and cancer processes. Attention was given to works that developed more effective approaches to the treatment of proinflammatory disease and cancer. The strong interdisciplinary focus will discuss biological systems at the level from a few molecules to the entire organism. Specific focus domain includes: Innate and adaptive immunity, cancer and cancer stem cell, genomic, proteomic and metabolic analysis, imaging, biophysics of immune and cancer response, computational modeling, non-linear analysis, statistical analysis, translational and disease models Types of articles: Viewpoint, commentaries, research letters, research articles, review and methodologies

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Natural deep eutectic solvents (NADES) are pharmaceutically accepted systems not only because they typically offer a serious enhancement of active pharmaceutical ingredient (API) solubility, but also due to their non-toxicity. This fortunate conjuncture allows for designing new media for escalation and controlled release of APIs. For example, composition optimisation of a series of NADES comprising choline chloride with multi-hydroxyl compounds was successfully performed for a set of sulphonamide-based drugs. These results confirmed that NADES in general, and the ones based on choline chloride and glycerol particularly, are an attractive alternative to traditional solvents for sulphonamide dissolution. Experiments augmented with in silico modelling can offer deeper insights into the thermodynamic characteristics of these systems and an explanation for the origin of the observed solubility enhancement. Research of this type offers universal resolutions to the problem of low solubility issues for many types of drugs. Of particular interest is that such screening is not restricted to artificial in vitro environments but can be also easily adopted for the study of modelled in vivo situations. One of very important and interesting examples is a new curcumin–NADES formulation preserving its beneficial properties even after dilution with FaSSIF solution, which mimicks intestinal absorption.

Graham Appleyard

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Wie reagieren Kommunen auf steigende Sozialhilfekosten? Am Beispiel der neun badenwürttembergischen Stadtkreise werden die sozialpolitischen Reaktionen - Zuschußkürzungen und Kostenverlagerungen - im Zeitraum 1980 bis 1992 untersucht. Einen weiteren Schwerpunkt bildet die Analyse finanzpolitischer kommunaler Reaktionen auf «fiscal stress» durch Sozialhilfekostenzuwächse und Einnahmenausfälle. Dabei wird insbesondere das «Cutback Management» der Städte Freiburg, Mannheim und Stuttgart betrachtet. Es zeigt sich, daß die «Flucht aus dem Haushalt» eine wichtige Anpassungsreaktion darstellt. Die Daten für die empirischen Untersuchungen wurden vor Ort erhoben und durch Informationen aus über hundert Interviews im sozialen, administrativen und politischen Bereich ergänzt.

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In this new Brookings Marshall Paper, Michael O’Hanlon argues that now is the time for Western nations to negotiate a new security architecture for neutral countries in eastern Europe to stabilize the region and reduce the risks of war with Russia. He believes NATO expansion has gone far enough. The core concept of this new security architecture would be one of permanent neutrality. The countries in question collectively make a broken-up arc, from Europe’s far north to its south: Finland and Sweden; Ukraine, Moldova, and Belarus; Georgia, Armenia, and Azerbaijan; and finally Cyprus plus Serbia, as well as possibly several other Balkan states. Discussion on the new framework should begin within NATO, followed by deliberation with the neutral countries themselves, and then formal negotiations with Russia.This book is made open access as part of the Knowledge Unlatched KU Select 2018: HSS Backlist Books