The outbreak of pneumonia infected by the novel coronavirus on January 23 Google translation of: http://www.nhc.gov.cn/xcs/yqtb/202001/5d19a4f6d3154b9fae328918ed2e3c8a.shtml Archived: https://archive.ph/gkpzs Release time: 2020-01-23 Source: Health Emergency Office As of 24:00 on January 22, our committee has received a cumulative report of 571 confirmed cases of pneumonia infected by the new coronavirus from 25 provinces (autonomous regions and municipalities) in China, including 95 cases of severe illness and 17 deaths (all from Hubei Province). A total of 393 suspected cases have been reported from 13 provinces (autonomous regions and municipalities). From 0 to 24:00 on the 22nd, 24 provinces (autonomous regions and municipalities) reported 131 new confirmed cases and 8 new deaths, including 5 males and 3 females. 13 provinces (autonomous regions and municipalities) reported 257 new suspected cases. A total of 25 provinces (autonomous regions and municipalities) have reported the epidemic. Confirmed cases reported abroad: 1 case in Hong Kong, China, 1 case in Macao, China, 1 case in Taiwan; 1 case in the United States, 1 case in Japan, 3 cases in Thailand and 1 case in South Korea. At present, 5897 close contacts have been traced, 969 people have been released from medical observation, and 4928 people are still under medical observation. Description of the condition of 17 deaths 1. Zeng XX, male, 61 years old, has a history of cirrhosis, myxoma and other diseases. Fever, cough, weakness began around December 20, 2019; He was hospitalized in the respiratory department of Wuhan Puren Hospital on the 27th, transferred to the ICU on the 28th, mechanically ventilated by tracheal intubation on the 30th, and transferred to the ICU of Jinyintan Hospital on the 31st; Transferred into a state of shock coma. ECMO support, anti-infection, anti-shock, and acidosis correction on January 1 are symptomatic supportive treatment. At 20:47 on January 9, the patient's heart rate suddenly dropped to 0, and the ECMO blood flow rate dropped rapidly to 0.2 liters per minute. Immediately rescued, by 23:13, the heart rate was still 0, and clinical death was declared. 2. Xiong XX, male, 69 years old, due to fever, cough for 4 days, aggravated with dyspnea for 2 days to visit Wuhan Red Cross Hospital, on January 3, 2020, he was intubated by a breathatic tube to assist breathing with a ventilator, and the myocardial enzyme profile continued to be abnormal. On January 4, he was transferred to Jinyintan Hospital. Admitted to the hospital for diagnosis of acute respiratory distress syndrome, respiratory failure, severe pneumonia, coma to be investigated, pleural effusion, and atherosclerosis of the aorta. CT of the patient's chest shows a large ground glass like a large area of both lungs. ECG illustration: ST-segment changes. After admission, intensive care, ventilator-assisted breathing, prone ventilation treatment, CRRT, anti-infection, liver protection and other symptomatic and supportive treatment, the condition did not improve, septic shock, microcirculation failure, coagulation dysfunction and internal environmental disorders worsened. At 00:15 on January 15, the patient's heart rate dropped to 0, and the patient's heart rate dropped to 0, and continuous norepinephrine, epinephrine, posterior pituitary lobulin, dopamine and other intravenous pumping were pumped into anti-shock therapy, and the patient was unable to resume spontaneous breathing and heartbeat, and by 0:45 bedside ECG showed complete cardiac arrest, and clinical death was pronounced. 3. Wang XX, male, 89 years old, has a history of hypertension, cerebral infarction, and brain softening. Due to urinary incontinence, he was admitted to the Department of Urology of Tongji Hospital on January 5, 2020, and was transferred to the emergency department on January 8 due to drowsiness and confusion. Examination reveals pulmonary infection (viral pneumonia) and acute respiratory failure. The physical examination on January 8 found that the patient was 77 mmHg and had hypoxia manifestations. CT of the lungs shows double lung patches, a small amount of pleural effusion on both sides, and pleural adhesions. Blood counts show progressively higher total white blood cells and low lymphocyte counts. On January 9, he was transferred to the fever clinic observation ward for rescue treatment and was given symptomatic supportive treatment. Ventilator-assisted positive pressure ventilation was given on 13 January. On 14 January, he developed lethargy and fluctuated between 50% and 85% of blood oxygen with ventilator-assisted ventilation. He was admitted to the infectious disease ward on 15 January. At 10:30 a.m. on January 18, the pre-hospital transfer Bp140/78mmHg, SPO2 85% under noninvasive ventilator-assisted ventilation. During the transfer, the patient developed respiratory cardiac arrest and continued to be rescued for 2 hours, and the treatment was ineffective and he was declared clinically dead at 13:37 on January 18, 2020. 4. Patient Chen X, male, 89 years old, has previous hypertension, diabetes, coronary heart disease, frequent ventricular premature beats, and coronary stent implantation. The patient became ill on 13 January 2020 and had no apparent predisposing panting, difficulty breathing spontaneously, and no fever 4 hours before present. On January 18, due to severe breathing difficulties, he was treated in the emergency department of Wuhan Union Hospital. The patient is elderly, positive for chlamydia pneumoniae pneumoniae, no A-B flow, positive for novel coronavirus, lung CT: typical changes in viral pneumonia. At 23:39 on January 19, 2020, his condition deteriorated and he died of ineffective rescue. 5. Li XX, male, 66 years old, previous COPD, hypertension, type 2 diabetes, chronic renal insufficiency, 2007 aortic artificial aortic replacement, 2017 abdominal aortic stenting, cholecystectomy, multi-organ dysfunction. The patient was admitted to Wuhan Iron and Steel General Hospital on January 16, 2020 due to intermittent cough, headache, fatigue and fever for 6 days. CT chest on 16 January showed bilateral pneumonia, fibrosis foci in the left upper lung, and small nodular shadow in the left upper lung. On January 17, he developed dyspnea, and blood gas analysis showed respiratory failure type 1, and symptomatic treatment such as mask oxygen inhalation, anti-infection, antiviral, and phlegm dissemination was given. At 10:10 a.m. on January 20, the patient was suddenly reduced to 40% of the phalangeal oxygen, and was given non-invasive ventilator-assisted ventilation therapy, and the family was again informed of severe respiratory failure, and again asked whether to undergo endotracheal intubation, and refused to undergo endotracheal intubation. At 10:35 a.m. on January 20, his condition deteriorated and he died of ineffective rescue. 6. Wang XX, male, 75 years old, was admitted to Wuhan Fifth Hospital at 17:19 on January 11, 2020 due to fever with cough, sputum cough and vomiting for 5 days. There is a previous history of hypertension and hip replacement. Admission body temperature 38.2 °C, with fatigue, insufficiency, cough, nasal congestion, dizziness, headache, no obvious chills, chills, muscle and joint soreness. CT chest suggests interstitial infection of both lungs. After admission to the hospital, he was reported to be critically ill, and he was given symptomatic treatment such as oxygen inhalation, anti-infection, anti-virus, sputum reduction, defervescence as appropriate, and rehydration. The patient's condition progressively worsened, and on 15 January he was transferred to the ICU for mechanical ventilation. He died at 11:25 on 20 January. 7. Yin XX, female, 48 years old, with diabetes and cerebral infarction. On December 10, 2019, there was no induced fever (38 °C), soreness and fatigue around the body, and cough and sputum were gradually appeared, and there was no improvement in the anti-infection treatment in the primary hospital for 2 weeks. On December 27, chest tightness and shortness of breath appeared, which were obvious after the activity, and Tongji Hospital gave non-invasive ventilation and conventional anti-infection treatment, and the condition still worsened. On December 31, he was transferred to Jinyintan Hospital and given symptomatic treatment measures such as high-flow oxygen inhalation in the nasal catheter, but the hypoxia state still did not improve significantly, and the condition still had a deteriorating trend. On January 14, 2020, chest CT showed diffuse organic changes in both lungs, some with traction bronchiectasis, especially in the lower lungs. At 11:50 a.m. on January 20, the tracheal tube was intubated, and analgesic and sedative treatment was given, and the finger oxygen saturation and blood pressure continued to decrease, followed by a decrease in heart rate, and finally the rescue was ineffective. 8. Liu XX, male, 82 years old, was admitted to Wuhan Fifth Hospital at 15:41 on January 14, 2020 due to cold and sore pain in his whole body for 5 days. ECG monitoring, non-invasive ventilator-assisted breathing, anti-infective, antiviral, and supportive symptomatic therapy. On 19 January, he developed slurred speech, weakness in his left limb, and contemplated stroke, progression of the disease worsened, and respiratory failure continued to worsen. At 00:30 on January 21, the patient's sudden progressive decrease in heart rate, heart sounds could not be heard, the aortic pulse disappeared, and he was immediately rescued, and the family still refused to intubate mechanical ventilation, continued rescue, the heart rate never recovered, and the clinical death was declared at 1:18. 9. Luo XX, male, 66 years old, no induced cough on December 22, 2019, mainly dry cough, no fever; Chest tightness and shortness of breath on December 31, which were evident after the activity, and went to the central hospital for treatment; On January 2, 2020, he was transferred to Jinyintan Hospital, and the imaging double lung lesions were diffuse, showing "white lung-like" changes. After admission, symptomatic treatment such as nasal high-flow oxygen is given, and refractory hypoxemia is difficult to correct. At 10:00 a.m. on January 12, he underwent tracheal intubation ventilator to assist breathing, sedation, body temperature 36.7 °C, respiratory distress, and continued active antibacterial therapy. On the same day, the patient's oxygenation improvement was not obvious, the concentration of oxygen inhaled by the ventilator was reduced to about 50%, and the arterial blood oxygen partial pressure was 80mmHg. The patient had a long course of illness, extremely poor immune function, and was at risk of septic shock, and died at 9:50 a.m. on January 21. 10. Zhang XX, male, 81 years old, was admitted to Wuhan First Hospital on January 18, 2020 due to fever for 3 days. Admission chest CT showed infectious lesions in both lungs, considering viral pneumonia, the patient's kidney function and lung infection continued to deteriorate, gradually appeared unconscious on the morning of January 22, 2020, the respiratory heart rate and blood pressure continued to decline and could not be maintained, the patient's family signed to refuse chest compression, tracheostomy and other rescue measures, the patient stopped breathing and heartbeat at 10:56 on January 22, and declared clinical death. 11. Zhang XX, female, 82 years old, has a history of Parkinson's disease for 5 years, oral medopa. Onset on January 3, 2020, due to "fever cough chest tightness and fatigue", he was treated at Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine on January 6, and was diagnosed with "viral pneumonia and respiratory failure". On January 20, he was transferred to Wuhan Jinyintan Hospital, his condition worsened, and on January 22, he underwent endotracheal intubation ventilator supportive treatment, respiratory failure did not improve, and he was declared clinically dead at 18:00 on January 22, 2020 by rescue ineffectiveness. 12. Zhou XX, male, 65 years old, was admitted to Wuhan First Hospital on January 11, 2020 due to shortness of breath and fatigue for 3 days. At the time of admission, the patient had difficulty breathing, chest tightness and shortness of breath, and an acutely ill face, and was diagnosed with severe pneumonia, acute respiratory failure, and liver function impairment. At 19:00 on January 21, heart rate and blood pressure decreased, the reflex of both pupils to light disappeared, and tracheal intubation, artificial chest compression, cardiac strengthening and other treatments were immediately performed, and by 19:54, the autonomic rhythm was not restored, and clinical death was declared. 13. Hu XX, female, 80 years old, onset on 11 January 2020. Due to fever, cough for 9 days, wheezing and breathing difficulties, he was admitted to China Resources Wugang General Hospital on January 18, 2020, and was transferred to Wuhan Jinyintan Hospital on January 20, 2020 due to positive nucleic acid of new coronavirus. He has a history of hypertension for more than 20 years, diabetes for more than 20 years, and a history of Parkinson's disease. After admission, he is critically ill, in intensive care, with anti-infection, ventilator-assisted breathing and symptomatic supportive therapy. However, the patient's condition did not improve, persistent hypoxemia, confusion, mechanical ventilator assisted breathing, on January 22, 2020 at 16:00 rescue ineffective, declared clinical death. 14. Lei XX, male, 53 years old. In early January, he was treated in a community hospital for fever, but the treatment was ineffective after several days, and fever, cough, and chest tightness worsened. On January 13, 2020, he went to the emergency department of Tongji Hospital, and CT showed double lung infection and respiratory failure; On January 18, he was critically ill, underwent non-invasive ventilator supportive treatment, and was transferred to Wuhan Jinyintan Hospital for isolation and treatment on January 20, 2020. After admission to the hospital after anti-infective anti-shock, ventilator-assisted respiratory support treatment, the patient's condition did not improve, respiratory failure continued to worsen, January 21 at 4 o'clock rescue was ineffective, declared clinical death. 15. Wang XX, male, 86 years old, was admitted to Xinhua Hospital on January 9, 2020 due to fatigue for 1 week. No fever, diabetes and hypertension and colon cancer 4 years after surgery. After admission, the lung CT showed multiple ground glass shadows in both lungs, obvious hypoxia, difficulty eating, rapid breathing, and lethargy. The family refused to be intubated, only inhaled oxygen through the nose, and stopped breathing at 17:50 on January 21, 2020, and declared clinical death. 16. Yuan XX, female, 70 years old. On January 13, 2020, the city's first hospital was admitted to the city due to continuous high fever. Confusion at the time of admission, acute appearance, decreased heart sounds, coarse breathing sounds in both lungs, and imaging results showed that the lung infection was severe. Severe pneumonia is considered with severe respiratory failure. That is, it is actively anti-infective, oxygen and other symptomatic treatment, but respiratory failure is difficult to correct. The patient was declared dead on 21 January 2020 due to respiratory failure. 17. Zhan XX, male, 84 years old. The patient was admitted to the Fifth Hospital of the City for treatment at 17:04 on January 9, 2020 due to fever, cough and panting for 3 days. There is a previous history of chronic bronchitis, unstable angina, coronary stenting, hypertension, gastrointestinal bleeding, renal insufficiency, hyperlipidemia, hyperuricemia, and lacunar cerebral infarction. Due to the worsening of the patient's condition and persistent high fever, the patient was transferred to the ICU on 18 January for anti-infection and symptomatic supportive treatment. At 10:16 on January 22, the patient stopped breathing, his heart rate gradually slowed down, and he was declared clinically dead at 10:52.