Michael YAO B.S. Applied Physics | Minor in Computer Science � linkedin.com/in/michael-yao-2021 � michaelsyao.com � +1 408 761 8752 � [email protected] � Pasadena, CA � California Institute of Technology Caltech fourth-year undergraduate and aspiring physician-scientist with a background in data-driven critical analysis applied to a multidisciplinary array of fields. Skills honed through 5+ years of research experience and rigorous scientific and technical training. Work showcases a ‘physics-derived,’ critical approach to problem-solving. Interested in the intersection of computational physics and translational medical technologies. � ACADEMIC MERITS July 2020 Class Rank : 3/233; In-Major Rank : 1/3 June 2020 Cumulative GPA : 4.20; Major GPA : 4.20 September 2019 MCAT (Medical College Admissions Test) : 520, 98th percentile (129 C/P, 129 CARS, 132 B/B, 130 P/S) October 2014 SAT : 2360, 99th percentile (800 Math, 760 CR, 800 WR, 12 Essay) June 2014 SAT Subject Test : 800 Math II, 800 Biology, 800 Chemistry � RESEARCH AND CLINICAL EXPERIENCE Present Undergraduate Research Fellow, � MIKHAIL SHAPIRO LABORATORY, Caltech October 2017 ∠ Microbial and T-cell engineering, design and optimization of thermally-controlled genetic circuits for transcriptional control ∠ Design of CRISPR-based systems for immunotherapeutic applications and gene regulation, with ap- plications for chimeric antigen receptor (CAR) T-cell engineering ∠ Manipulating cellular water diffusivity to enhance MRI image contrast ∠ Theoretical modeling of nanoscale biomagnetic hysteresis and cellular responses to external magne- tic fields Larson Scholar Fellowship Ronan Armann Mack Research Fellowship John Stauffer Research Fellowship July 2017 Research Assistant, DIETER GRUNERT LABORATORY, Department of Otolaryngology, UCSF June 2015 ∠ Directed stem cell differentiation. Gene editing of the human GCM2 gene in CFBE41o- immortalized cells and primary induced pluripotent stem cells (iPSCs) to introduce genetically expressed markers to track gene expression in the parathyroid differentiation pathway ∠ Seamless gene correction of Class II W1282X and ∆F508 CF genetic mutations 2017 Regeneron Science Talent Search Semifinalist July 2019 Preceptorship Student, CITY OF HOPE MEDICAL CENTER, Duarte, CA June 2019 ∠ Four-week preceptorship program (100+ hours) shadowing doctors and professionals in academic medicine from various subspecialties in medicine, including pathology, hematology, clinical trial re- search, medical oncology, palliative care, surgery and associated surgical subspecialties ∠ Learned from various MD-PhD physician scientists about their respective career paths and life expe- rience, reaffirming my desire to become a physician scientist July 2018 Shadowing Student, HUNTINGTON HOSPITAL, Pasadena, CA June 2018 ∠ Six-week preceptorship program (200+ hours) shadowing physicians and hospitalists from various specialties in medicine, including pulmonary intensive care, emergency medicine, pediatric internal medicine, opthalmology, cardiology internal medicine, diagnostic and interventional radiology, pa- thology, neurosurgery, general surgery and associated surgical subspecialties � PROGRAMMING LANGUAGES + GENERAL Java ○ ○ ○ ○ ○ Matlab ○ ○ ○ ○ � ∠ Languages : English · Spanish · Chinese Python ○ ○ ○ ○ ○ HTML/CSS ○ ○ ○ � � ∠ OS : Linux · Mac · Windows C ○ ○ ○ ○ ○ C++ ○ ○ ○ � � ∠ IDEs : Jupyter · IntelliJ · Eclipse · Vim · repl.it ∠ Computational Tools : Mathematica · R MICHAEL YAO - CV 1 � PUBLICATIONS AND MANUSCRIPTS 2020 Abedi, MA† ; Yao, M† ; Mittelstein, DR; Bar-Zion, A; Swift, M; Lee-Gosselin, A; Shapiro, M. Thermal bioswitches for localized activation of microbial immunotherapies (In Preparation for Submission, † Equal contribution) 2020 Yao, M ; Uhr, L; Daghlian, G; Amrute, JM; Deshpande, R; Mathews, B, MD; Patel, SA, MD; Henri, R, MD; Liu, G, MD; Reierson, K, MD; Johnson, G, MD. Demonstration of a longitudinal action medical mission (LAMM) model to teach point-of-care ultrasound in resource-limited settings (Published in � POCUS Journal) 2019 Maw, AM, MD; Galvin, B, NP; Henri, R, MD; Yao, M ; Exame, B, MD; Fleshner, M, MD; Fort, MP, MD; Morris, MA, MD. Stakeholder perceptions of point-of-care ultrasound implementation in resource-limited settings (Published in � Diagnostics) � HONORS AND AWARDS 2020 Larson Scholar Fellowship, Caltech � About the Award 2020 Jack E. Froehlich Memorial Award, Caltech � About the Award 2020 Henry Ford II Scholar Award, Caltech � In the News 2020 McLean Scholarship, Caltech 2019 Richter Memorial Fund Scholarship, Caltech (Supports Over 60% of Tuition Costs) 2019 Ronan Armaan Mack Research Fellowship, Caltech (Summer Research Fellowship 2018 USC Stevens Center for Innovation Showcase Competition Finalist, University of Southern California 2018 Doris S. Perpall Speaking Competition Semifinalist, Caltech 2018 John Stauffer Research Fellowship, Caltech (Summer Research Fellowship) 2018 Judy Oliphant Memorial Scholarship, Diablo Valley Assistance League � In the News 2017 National Merit Scholar, NMSC 2017 United States of America Biology Olympiad (USABO) Semifinalist 2016 United States National Chemistry Olympiad (USNCO) Honors (Top 150 Nationally) � PROJECTS ATRIACONNECT, INC. 2018 - PRESENT � https://www.atriaconnect.org � What is AtriaConnect? A Video Guide CEO and co-founder of a 501(c)(3) nonprofit organization. AtriaConnect is a startup medical nonprofit centered on equipping resource-limited communities with both state-of-the-art technologies and the knowledge on how to use them. Since the group was founded in April 2018 at Caltech, we have... ∠ successfully trained four Haitian physicians in a community hospital in Haiti how to incorporate point-of-care ultrasound (POCUS) into their individual medical practices ∠ raised over $40,000 USD in revenue to fund our organization’s work ∠ been accepted into the Sling Health Accelerator Program in 2018, and presented at the 2018 USC Stevens Center for Innova- tion Symposium ∠ established a growing network of students and doctors that spans 3 countries, 15 institutions, and 18 physicians ∠ partnered with companies such as Philips Healthcare and Innovating Imaging Technologies (IIT) Health Tech POCUS Radiologic Education Medical Outreach CHATTER MAY 2020 - PRESENT � Landing Page (In Progress) Website and mobile iOS app to make information on contraceptives more accessible. Users are able to see what their (anony- mized) social media contacts and community members use for birth control and sexual health. By making contraceptive usage data more transparent and easily accessible, we hope to encourage more engaged conversations between patients and their healthcare providers. This project is a collaboration between the � USC EMERGE Lab and � AtriaConnect Swift Xcode Firebase HTML/CSS Jekyll RECOMBINATION CHECKER JUNE 2020 � Repository Description Program that takes a DNA sequence string and checks for potential sites of DNA recombination given a set of parameters. Takes into account minimum homology length, maximum allows homology mismatch, and predicted DNA secondary structures to output potential sites where DNA could be excised due to sequence homology Java Python 3 MCAT STUDY GUIDE JUNE 2019 - DECEMBER 2019 � github.com/myaomeow/MCAT_Study_Guide_SU2019 Publically available, condensed study guide (150 pages) written to help students prepare for the Medical College Admissions Test (MCAT). Used personally and by students I have tutored previously LATEX MICHAEL YAO - CV 2 � OUTREACH AND VOLUNTEER INVOLVEMENT 2020 President of � Caltech’s Medlife student club, member since 2017. Organized science exhibition days at local high schools, lab tours for high school students, clinical volunteering opportunities, community cancer symposiums, etc 2020 Editor-in-Chief of Caltech’s undergraduate research journal, editor since 2017 2020 Current tutor for high school students as a part of Caltech’s RISE Tutoring Program, and an independent tutor and college application essay editor 2019 Member of the Academics and Research Committee at Caltech since 2017, and member of the Core Cur- riculum Steering Committee during the 2018-2019 school year. Acting liaison between faculty and under- graduates at Caltech to improve the quality of academic life on campus 2018 Student Ambassador for Caltech’s Summer Undergraduate Research Program. Established a safe and in- clusive space for students in summer research programs at Caltech, and offered resources to settle disputes and overcome difficulties throughout the summer. � TEACHING AND MENTORING Present Teaching Assistant, CALTECH, Pasadena, CA January 2019 ∠ ACM95ab : Differential Equations and Complex Analysis (Spring 2021, Winter 2021, Spring 2020) ∠ Ph125a : Graduate Quantum Mechanics (Fall 2020) ∠ Ph12ab : Waves, Quantum Mechanics (Fall 2019, Winter 2020) ∠ CS24 : Introduction to Computing systems (Fall 2019) ∠ Ph1bc Analytical : Special Relativity and Electromagnetism (Winter 2019, Spring 2019) Grading Office Hours Writing Solutions to Problems Present Deans’ Tutor, CALTECH, Pasadena, CA October 2018 ∠ Ch1b : General Chemistry, Deans’ Tutor Office Hour Session Lead (Winter 2019) ∠ Ch1a : General Chemistry ∠ Ph1abc Analytical : Freshman Physics (Classical Mechanics, Special Relativity and Electromagnetism) ∠ Ma1abc : Freshman Mathematics (Proofs, Linear Algebra and Multivariable Calculus) ∠ Ma2 : Differential Equations ∠ Ma3 : Probability and Statistics ∠ Ch41ab : Organic Chemistry ∠ ACM95ab : Complex Analysis and Differential Equations ∠ Ph12abc : Introduction to Waves, Quantum Mechanics, and Thermodynamics ∠ CS1 : Introduction to Computer Science ∠ CS2 : Introduction to Data Structures Sample Teaching Modules ∠ Stacks and Queues : I introduce both the stack and queue interfaces in Java programming, in addition to their potential applications. repl.it plugin integration allows for students to try their code as they’re lear- ning about the algorithms, and using real-life situations proves to be particularly effective in explaining ana- logous abstract computer concepts to students. ∠ Practicing the Fundamentals of Integration : This module is intended for students to be able to review the fundamentals of integration in AP Calculus AB, up until u-substitution. Hidden solutions and easy-to-read explanations are included to encourage students to attempt all of the problems. ∠ Conway’s Game of Life : A mesmerizing program with an interactive user interface that allows students to code their own project using very minimal prerequisite knowledge of Java. This mini-project is intended to give students a glimpse of the power of programming and encourage them to continue improving their coding skills. � REFERENCES Mikhail Shapiro, PhD Gordon Johnson, MD Justin Lee Professor of Chemical Engineering, CALTECH Legacy Health, PORTLAND, OR MD-PhD Candidate, CALTECH-UCLA MSTP � [email protected] � [email protected] � [email protected] � +1 626 395 8588 � +1 503 290 4960 � +1 818 731 7280 MICHAEL YAO - CV 3
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