AQA Biology Paper 1 Higher Combined Science Predicted Paper 2022 Name ……………………………………………… Date ……………………………………………… 1 hour 15 minutes allowed Similar to your real exam, each question in this gets harder towards the end of the question, so if you find you can’t do the last part of a certain question, try the next question – they all start off easier, and then get harder. Grade boundaries These are VERY rough guesses! Getting an 8 or 9 on this paper does not guarantee you the same mark in the exam. • 9 55 • 8 45 • 7 35 • 6 25 • 5 15 The information from the exam board gives us a broad overview of what is covered in the exam. If a topic is not listed as a ‘major focus’, it can still come up in a question, but that question might not be worth many marks. There are questions in this paper that cover topics that are not a ‘major focus’ for the exam, but don’t let that worry you! Primrose Kitten – YouTube Tutorials for GCSE and A-Level 1 Exam Analysis Advanced What do you Marks Marks Question Topic information for need to do to available gained 2022 improve? Not listed as a 1 12 Cells ‘major focus’ 2 16 Cell division Cell division Required Practical 3 22 Photosynthesis Activity 5 and Photosynthesis Required Practical Activity 3; Required Practical 4 14 Enzymes Activity 4 and animal tissues, organs and organ systems Bacterial Not listed as a 5 6 infections ‘major focus’ Total 70 Primrose Kitten – YouTube Tutorials for GCSE and A-Level 2 Question 1 a) Below is an animal cell. Give the names of parts A-D A …………………………………………………… (1 mark) B …………………………………………………… (1 mark) C …………………………………………………… (1 mark) D …………………………………………………… (1 mark) b) State three differences between prokaryotic and eukaryotic cells. (3 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 3 c) Nearly all animal cells contain a nucleus. Give one type of cell which does not. (1 mark) …………………………………………………………………………………………………………………………………… d) Explain the purpose of the nucleus within the cell. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… e) Many cells within the body are specialised. Explain what is meant by “specialised”. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 4 Question 2 Mitosis is the process of cell division. a) Complete the paragraph below to accurately describe mitosis. (5 marks) During cell division, cells go through a series of stages known as the ………………………………… This process involves a doubling in the number of ………………………, which are then pulled to each end of the cell as the …………………………… also divides. This results in ……………………… identical ……………… cells. b) In young mammals, cell division occurs to facilitate growth and development. Suggest a purpose for cell division in mammals. (1 mark) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… c) Explain why the resulting cells are identical. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… d) Explain what is meant by the term “stem cell”. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 5 e) Evaluate the social, ethical, religious and medical issues associated with the use of stem cells in medical treatment and research. You should arrive at a reasoned conclusion in your answer. (6 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 6 Question 3 a) Plants can undertake both respiration and photosynthesis. Sketch a graph to show how the levels of these processes change over the course of 24 hours. (3 marks) b) Anaerobic respiration in plants is useful in the food industry. Give the name of the process of anaerobic respiration in yeast. (1 mark) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… c) A student wants to determine the rate of anaerobic respiration in yeast that occurs at different temperatures. Describe a method that could be used to determine the rate of anaerobic respiration. (4 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 7 d) Suggest a suitable range and interval of temperatures to test. Explain your answers. (4 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… e) When undertaking this experiment, it was found that no respiration took place at 80°C. Explain why. (2 marks) ………………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………………… f) A student stated that light was important for photosynthesis and that the colour of the light didn’t matter. They set up an experiment to test this with the question “how does the colour of light affect the rate of photosynthesis?” They counted the number of bubbles released when pond weed had different colour lights shone on it. i. State the independent variable in this experiment (1 mark) ………………………………………………………………………………………………………………………… ii. Describe two ways the students can ensure that the results from this experiment can be compared with other similar experiments. (4 marks) ………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 8 g) The results that the student obtained are below. Colour of Bubbles released in 3 minutes light Test 1 Test 2 Test 3 Mean White 51.0 53.5 49 51.16 Red 43.0 41 39 41 Blue 19.0 21.0 25 21.6 Green 14.0 31.0 12 i. Comment on the error that the student has made when recording the data. (1 mark) ………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… ii. Complete the table by calculating the mean value for green light. (2 marks) Primrose Kitten – YouTube Tutorials for GCSE and A-Level 9 Question 4 a) Explain what is meant by the term “enzyme”. (2 marks) ………………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………………… b) pH can affect the rate of enzyme-controlled reactions. State two other factors which affect the rate. (3 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… c) When investigating the effect pH has on enzyme-controlled reactions, the activity of amylase can be monitored by a colour change. When carrying out this experiment, a student observed that both low pH and high pH showed the same results. Explain why. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… d) The end point for this experiment is a colour change. Explain why is it important to have a “zero time” sample. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… Primrose Kitten – YouTube Tutorials for GCSE and A-Level 10 e) Many enzymes in the digestive tract help to break down large, complex molecules into smaller, simpler ones. Suggest why this is needed. (2 marks) …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………………… f) There are a number of enzymes that work in the digestive system. A student wanted to test a sample before and after enzymes had been added. Read the following method and complete the results table. (3 marks) • Cut up cubes of potato and boil them to make a mash • Take 1cm3 of mash and mix it with 5cm3 of water to make a solution • Label three tubes (A, B and C) and add 1cm3 of mash solution • Warm in a water bath and add 1cm3 of the enzyme solution • Incubate for 5 minutes • After 5 minutes, test samples with Benedict’s solution and iodine solution • Record results in the table below Result with Result with Tube Enzyme added Benedict’s iodine Solution solution A None B Amylase C Lipase Primrose Kitten – YouTube Tutorials for GCSE and A-Level 11 Question 5 Tuberculosis (TB) is caused by a bacterial infection with Mycobacterium tuberculosis, and is spread by coughs and sneezes. a) The BCG vaccination is offered to people to prevent infection with TB. Explain how a vaccination can protect people. (3 marks) ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… b) If a person does get infected with TB, suggest a type of medicine that could be given to them. (1 mark) ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… c) Give two other examples of bacterial infection. (2 marks) ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………… End of Paper!! You’re awesome!! Primrose Kitten – YouTube Tutorials for GCSE and A-Level 12 Answers Question Answer Guidance 1a A-Nucleus One mark B-Mitochondria for each C-Cytoplasm D-Ribosomes 1b - Prokaryotes are smaller One mark - Prokaryotes have no nucleus for each - Prokaryotes contain plasmids 1c Red blood cell 1d - Storing DNA One mark - Idea of controlling/acting as a control centre of the for each cell 1e - Physical or chemical changes One mark - Being suited to a specific purpose for each 2a Cell cycle, chromosomes, nucleus, two, daughter One mark for each 2b Repair 2c - DNA is being copied One mark - Idea of genetically identical for each 2d - A cell which is not yet specialised One mark - Idea that this cell can become many different things for each 2e A1-2M if answer addresses only basic concerns of 1/2 of Level the areas without using specialist terminology. assessed A3-4M if answer addresses only basic concerns of 2/3 of marking the areas without using specialist terminology, or which addresses only one with some detail and terminology. A5-6M if answer addresses multiple areas in detail, with the use of specialist terminology - an opinion with reason. - Treatment of type one diabetes / paralysis - Treatment of any other suitable condition - No guarantee of successful treatment - Hard to find adult stem cell donors - Adult stem cells only differentiate into a narrow range of cells - Embryonic stems cells are from embryos, which some people view as already a person - Embryonic stem cells differentiate into a wide range of cell types - Embryonic SCs can come from stored umbilical cords (collected at birth, storage is expensive) - Embryonic SCs come from by-products of IVF - Private treatment can be expensive Primrose Kitten – YouTube Tutorials for GCSE and A-Level 13 3a One mark for labelled axis One mark for shape of each line - 3b - Fermentation 3c - Collect gas produced One mark - Compare volumes at different temperatures for each - Incubate mixture and different temperatures bullet point - Specific way of collecting gas named, e.g., measuring cylinder and delivery tube or gas syringe. 3d - Range needs to sit within 10°C and 60°C, must be One mark written in x°C to y°C format. for each - Too cold the mixture will freeze, too hot it will be bullet point dangerous - Interval between 5°C and 15°C - Too small will be hard to control in a classroom and too large will be hard to see any change 3e - Enzymes One mark - Denatured for each bullet point 3fi Colour of light 3fii Control variable listed must be accompanied by how it will 2 marks for be controlled. control variable and - Light intensity 2 marks for - Keeping the light the same distance from the plant linked - Temperature measure - No change in heating or cooling, do not heat experiment - Size of leaves - Same plant will be used for each experiment Others can be allowed marks Primrose Kitten – YouTube Tutorials for GCSE and A-Level 14 3gi Different resolution used (number of decimal places) so you can’t count part of a bubble. Should all be whole numbers. 3gii - Do not include anomalous result One mark - 13 for each bullet point 4a - Biological One mark - Catalyst for each bullet point 4b - Temperature One mark - Concentration of enzyme for each - Concentration of substrate bullet point 4c - Amylase not working at both low and high pH - Enzyme denatured 4d - Colour comparison - Control 4e - They can move into the bloodstream One mark - Transported around the body or to useful for each places/organs bullet point 4f 1 mark for Result with Result with each correct Enzyme Tube Benedict’s iodine row added Solution solution Black/brown A None No change colour seen Blue No colour B Amylase solution change goes red Black/brown C Lipase No change colour seen 5a - Small dose of inert disease delivered - Body remembering how to make antibodies - Antibodies specific to disease 5b Antibiotics 5c - Salmonella - Gonorrhoea Primrose Kitten – YouTube Tutorials for GCSE and A-Level 15
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