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Justice and Vulnerability in Europe contributes to the understanding of justice in Europe from both a theoretical and empirical perspective. It shows that Europe is falling short of its ideals and justice-related ambitions by repeatedly failing its most vulnerable populations.

Yukon Department of Education

Sofa Go-Go

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Stress proteins or heat-shock proteins (HSP) are evolutionary conserved proteins present in every prokaryotic and eukaryotic cell. Their main function is to protect cells and proteins from damage under stressful circumstances. The latter circumstances do include the cell and protein damaging effects of inflammation. The discovery of mycobacterial HSP60 being a critical antigen in the model of adjuvant arthritis, has led to studies that showed the immuno-dominance of microbial HSP60 and the potential of the microbial HSP induced repertoire of antibodies and T cells to cross-recognize the self-HSP homologues of stressed cells. Since then, the research in the immunology of stress proteins started to comprise a widening spectrum of topics with potential medical relevance. Interestingly, since stress proteins have their activities in both innate and adaptive immunity, they are key elements in the cross-roads between both arms of the immune system. Stress proteins or HSP can be considered as functional 'biomarkers' of inflammation. They are up-regulated locally during inflammation and interestingly, they seem to function as targets for anti-inflammatory regulatory T cells. In experimental models of autoimmunity, mainly arthritis, administration of HSP peptides have been shown to suppress disease. First clinical trials have shown the anti-inflammatory nature of T cell responses to Hsp. In type I diabetes and in rheumatoid arthritis, parenteral and oral administration of Hsp peptides were shown to induce a bias in pro-inflammatory T cells, switching them in the direction of regulatory cytokine production (IL4, IL5 and IL10). In addition a raised level of a marker of natural T regulatory cells, the transcription factor FoxP3, was noted in the RA trial. Other inflammatory diseases or diseases with inflammatory components which feature the immune imprint of the up-regulated Hsp are atherosclerosis, inflammatory bowel diseases, multiple sclerosis and atopic diseases such atopic dermatitis and allergic asthma.

Danny Harper

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Seka Black

Adrian Krebs

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This book, entitled “Mesoporous Metal Oxide Films”, contains an editorial and a collection of ten research articles covering fundamental studies and applications of different metal oxide films. Mesoporous materials have been widely investigated and applied in many technological applications owing to their outstanding structural and physical properties. In this book, important developments in this fast-moving field are presented from various research groups around the world. Different preparation methods and applications of these novel and interesting materials have been reported, and it was demonstrated that mesoporosity has a direct impact on the properties and potential applications of such materials. The potential use of mesoporous metal oxide films and coatings with different morphology and structures is demonstrated in many technological applications, particularly chemical and electrochemical sensors, supercapacitors, solar cells, photoelectrodes, bioceramics, photonic switches, and anticorrosion agents.

Alexander Wren

Coast Dental

A dental clinic Singapore is an incredibly important space to visit on a regular basis. Receiving regular care from a licensed dentist can help prevent the onset of serious dental problems, and ensures excellent oral health overall. Dental clinicsingapore provide comprehensive care for both children and adults by assessing the patients for cavities, gum disease, tooth decay, and more. For those who have experienced traumatic dental events or are dealing with chronic dental issues, the comprehensive tools and services provided in a dental clinic Singapore can be invaluable in restoring comfort and peace of mind. With proper preventive care and treatments available in a professional setting, maintaining healthy teeth and gums is within reach for all individuals. click site : https://www.coastdental.com.sg

TG Plein

I.S.A. Corporation

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The Mulukī Ain of 1854—the law code with constitutional features drafted at the initiative of Prime Minister Jaṅga Bahādura Rāṇā—is the foundational legal text for modern Nepal. It covers almost every aspect of public, criminal, private and religious law, ranging from the organisation of the state and courts to murder and other delicts, the workings of the caste system and the joint family, matters of purity and penance, customary law, widow-burning and witchcraft. As such, the Mulukī Ain is a unique source not only for the political, social and economic life of 19th-century Nepal, but also for the place of traditional Hindu jurisprudence in South Asian legal cultures.

HOLY SPIRIT

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Kunal Solanki

Uncover London's hidden gems with our guide to the top 20 must-visit spots for students. Explore unique attractions, cozy cafes, and secret hangouts perfect for student life.

Altigreen

Charles Frederick Moore (editor)

PD-US

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This open access volume makes an important contribution to the ongoing research on hope theory by combining insights from both its long history and its increasing multi-disciplinarity. In the first part, it recognizes the importance of the centuries-old reflection on hope by offering historical perspectives and tracing it back to ancient Greek philosophy. At the same time, it provides novel perspectives on often-overlooked historical theories and developments and challenges established views. The second part of the volume documents the state of the art of current research in hope across eight disciplines, which are philosophy, theology, psychology, economy, sociology, health studies, ecology, and development studies. Taken together, this volume provides an integrated view on hope as a multi-faced phenomenon. It contributes to the further understanding of hope as an essential human capacity, with the possibility of transforming our human societies.

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