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The fourth edition of the Osdotta seminar, was held in Turin from 10-13 September 2008. The Seminar, set up as a moment of reflection about the tendencies that characterize the internal research of the Technology of Architecture, expanded its area of interest, opening up to different and wider horizons for new objectives of research. The program of the three days of meetings developed, as in the preceding editions, with an organic series of thematic tables merging in the final round table that hosted the discussions and the verification of the three external valuators.

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Bertrand Russell

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The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.

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In vitro, in vivo, and in silico preclinical models hold a widely acknowledged potential, yet complex limitations. For this reason, which has been known for a long time by experimenters and modelers, the translation of “science products” to the clinic is still far. Therefore, there is a raising awareness of the need to bridge this gap by developing integrated and innovative models. Organ and tissue bioengineering is an ideal approach to foster innovative strategies in significant research and clinical areas. Similarly, in translational neuroscience research, this challenge has been taken up by intriguing fish models. However, much research based on novel methodologies has still to be performed to get the bench closer to the bedside.

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Irrespective of whether we use economic or societal metrics, the Internet is one of the most important technical infrastructures in existence today. It will be a catalyst for much of our innovation and prosperity in the future. A competitive Europe will require Internet connectivity and services beyond the capabilities offered by current technologies. Future Internet research is therefore a must. This book is published in full compliance with the Open Access publishing initiative; it is based on the research carried out within the Future Internet Assembly (FIA). It contains a sample of representative results from the recent FIA meetings spanning a broad range of topics, all being of crucial importance for the future Internet. The book includes 32 contributions and has been structured into the following sections, each of which is preceded by a short introduction:Foundations: architectural issues; socio-economic issues; security and trust; and experiments and experimental design. Future Internet Areas: networks, services, and content; and applications.

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Walter Crane

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