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In the world of therapeutic bodywork, there are many modalities designed to relieve stress, ease tension, and promote physical and mental wellbeing. One such approach that has gained attention in recent years is the Nuru massage — a form of body-to-body therapeutic touch that emphasizes fluid movement and deep relaxation. If you’re curious about this service and what sets it apart, this microblog breaks down the essentials and gives you some thoughtful insight — whether you’re exploring it for t
Beyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibiotics, many scientists are currently investigating biosynthetic aspects of antibiotic production in actinomycetes. Since the emergence of next-generation sequencing technologies, the field of antibiotics research has experienced a remarkable revival. These bacteria have the potential to produce more antibiotics than previously thought possible. Some antibiotics are produced in standard media, while others require the presence of a specific signaling molecule in the medium. Others, however, are only produced when the native regulation of the biosynthesis gene cluster is overruled. This book covers topics in the field of antibiotic-producing actinomycetes. The following tops are addressed: - Approaches to access novel antibiotic producers for novel natural compounds - Omics and genome mining approaches for the discovery of novel natural compounds - Analyses and genetic engineering of antibiotic biosynthesis - Regulation of the secondary metabolism in actinomycetes
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A hallmark of inflammation is the accumulation of leukocytes, which can serve to remove pathogens and necrotic tissue, but may also damage healthy tissue and exacerbate the inflammatory response. Our understanding of leukocyte recruitment in inflammation was revolutionized in the late 1980s by the discovery of chemokines (chemotactic cytokines), a family of small, secreted proteins that induce migration of selective subsets of leukocytes. Shortly afterwards, chemokines were found to exert their functions through the now familiar chemokine receptors, members of the G protein-coupled receptor superfamily. As their physiological and pathological functions were elucidated, chemokine receptors have become popular targets for drug development in inflammatory diseases as well as cancer metastasis and HIV infection. Extensive research has revealed that the functions of chemokines and their receptors are regulated at numerous levels, including: genetic mutations/polymorphisms; control of expression levels; ligand internalization via functional or decoy receptors; intrinsic selectivity of chemokine-receptor binding; hetero- or homo-oligomerization of chemokines or of receptors; alternative signalling pathways; interaction of chemokines with glycosaminoglycans; post-translational modifications; and binding to pathogen-derived inhibitors. This Special Issue of IJMS focused on the natural and pharmacological mechanisms by which the activities of chemokines and their receptors can be regulated.
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Mystical Rhythms: Unveiling the Voodoo Ceremonies of Haiti" takes you on a mesmerizing journey deep into the heart of Voodoo, the spiritual tapestry of Haiti. This immersive documentary showcases the captivating rituals, vibrant dances, and ancient traditions that define Voodoo ceremonies. Through stunning visuals, intimate interviews, and expert insights, viewers will gain a profound understanding of the sacred practices, the significance of the Lwa (deities), and the profound spiritual connections forged within these mystical gatherings. Discover the rich cultural heritage and the resilience of the Haitian people as they celebrate and preserve their ancestral beliefs. Join us as we unravel the enigmatic world of Voodoo ceremonies, where tradition, spirituality, and community converge.
The secrets to becoming a top-tier Data Architect with comprehensive preparation materials, practice exams, and question-answer sets. Master the art of data modeling, database management, and analytics to propel your career forward. Ace your interviews with confidence and showcase your expertise in designing and implementing robust data systems.
A queen wall bed with a desk makes it easy to switch between work time and rest time. When the bed is folded up, the desk is ready for writing, meetings, or reading. When work is done, the desk closes, and the bed opens. This simple change helps the mind understand when it is time to work and when it is time to relax. This clear routine supports a healthier work-life balance.
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Introducing Weight Loss and You - How to Start Losing Weight. Inside this eBook, you will discover the topics about how can weight loss benefit you, things you should know before starting any weight loss program and do weight loss diet programs really work.
Learn expert tips from children's dentists on preventing cavities in kids. From establishing good oral hygiene habits to choosing tooth-friendly snacks, discover essential advice for maintaining your child's dental health.
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Vinyl tools are indispensable companions for anyone venturing into the world of working with Vinyl tools and materials. As versatile as the vinyl itself, these tools are meticulously designed to enhance precision, efficiency, and overall craftsmanship throughout your creative process.