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Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

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Albedo is a known and documented phenomenon, defined as the reflectivity of a surface, i.e., the ratio of reflected light energy to incident light energy. It is a dimensionless quantity, used in particular in agro-forestry, urban environment, cryosphere and geology. It is an Essential Climate Variable (ECV), deemed extremely meaningful to compute the earth heat balance. The albedo of natural surfaces varies largely, especially in the visible, with the lowest values found for water bodies and dense vegetation canopies and the highest values for desert and snow. It also changes with the angular distribution and spectral composition of the incident radiation and with the surface moisture. Satellite observations allow consistent measuring of the surface albedo at continental scale over a short period of time. Long-term series of surface albedo are good indicators of climate change, especially over glaciers and polar caps. On the other hand, the albedo of bare soil provides a good diagnostic of their degradation. The reliability of satellite albedo is verified against ground-based radiometers and UAV, which also serves to calibrate the instruments embarked on space-borne observing systems and check the quality of the atmospheric correction.

Avni Khanna

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There has been an enormous increase in interest in the use of evidence for public policymaking, but the vast majority of work on the subject has failed to engage with the political nature of decision making and how this influences the ways in which evidence will be used (or misused) within political areas. This book provides new insights into the nature of political bias with regards to evidence and critically considers what an ‘improved’ use of evidence would look like from a policymaking perspective.Part I describes the great potential for evidence to help achieve social goals, as well as the challenges raised by the political nature of policymaking. It explores the concern of evidence advocates that political interests drive the misuse or manipulation of evidence, as well as counter-concerns of critical policy scholars about how appeals to ‘evidence-based policy’ can depoliticise political debates. Both concerns reflect forms of bias – the first representing technical bias, whereby evidence use violates principles of scientific best practice, and the second representing issue bias in how appeals to evidence can shift political debates to particular questions or marginalise policy-relevant social concerns.Part II then draws on the fields of policy studies and cognitive psychology to understand the origins and mechanisms of both forms of bias in relation to political interests and values. It illustrates how such biases are not only common, but can be much more predictable once we recognise their origins and manifestations in policy arenas.Finally, Part III discusses ways to move forward for those seeking to improve the use of evidence in public policymaking. It explores what constitutes ‘good evidence for policy’, as well as the ‘good use of evidence’ within policy processes, and considers how to build evidence-advisory institutions that embed key principles of both scientific good practice and democratic representation. Taken as a whole, the approach promoted is termed the ‘good governance of evidence’ – a concept that represents the use of rigorous, systematic and technically valid pieces of evidence within decision-making processes that are representative of, and accountable to, populations served.

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Pratyush Kumar Sahoo

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Scraps of Hope in Banda Aceh examines the rebuilding of the city of Banda Aceh in Indonesia in the aftermath of the celebrated Helsinki-based peace mediation process, thirty years of armed conflict, and the tsunami. Offering a critical contribution to the study of post-conflict politics, the book includes 14 documentary videos reflecting individuals’ experiences on rebuilding the city and following the everyday lives of people in Banda Aceh.Marjaana Jauhola mirrors the peace-making process from the perspective of the ‘outcast’ and invisible, challenging the selective narrative and ideals of the peace as a success story. Jauhola provides alternative ways to reflect the peace dialogue using ethnographic and film documentarist storytelling.Scraps of Hope in Banda Aceh tells a story of layered exiles and displacement, revealing hidden narratives of violence and grief while exposing struggles over gendered expectations of being good and respectable women and men. It brings to light the multiple ways of arranging lives and forming caring relationships outside the normative notions of nuclear family and home, and offers insights into the relations of power and violence that are embedded in the peace.Marjaana Jauhola is senior lecturer and head of discipline of Global Development Studies at the University of Helsinki. Her research focuses on co-creative research methodologies, urban and visual ethnography with an eye on feminisms, as well as global politics of conflict and disaster recovery in South and Southeast Asia.This publication has received a subsidy for scientific publishing granted by the Ministry of Education and Culture from the proceeds of Veikkaus, distributed by the Federation of Finnish Learned Societies.

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Oteng Kwame Appiah-Nti

MIT

The late Comfort Abena Aboagyewaa was born to the parents of the late Mr. Kwame Asante and Late Yaa Bedua in the year 12th February,1932 at Bediase in the Eastern Region of Ghana. She was their first child among her siblings of six i.e two (2) females and four (4) males, who brought much joy to them.

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