Yeasts are truly fascinating microorganisms. Due to their diverse and dynamic activities, they have been used for the production of many interesting products, such as beer, wine, bread, biofuels, and biopharmaceuticals. Saccharomyces cerevisiae (brewers’ or bakers’ yeast) is the yeast species that is surely the most exploited by humans. Saccharomyces is a top-choice organism for industrial applications, although its use for producing beer dates back to at least the 6th millennium BC. Bakers’ yeast has been a cornerstone of modern biotechnology, enabling the development of efficient production processes. Today, diverse yeast species are explored for industrial applications. This Special Issue “Yeast Biotechnology 2.0” is a continuation of the first Special Issue, “Yeast Biotechnology” (https://www.mdpi.com/books/pdfview/book/324). It compiles the current state-of-the-art of research and technology in the area of “yeast biotechnology” and highlights prominent current research directions in the fields of yeast synthetic biology and strain engineering, new developments in efficient biomolecule production, fermented beverages (beer, wine, and honey fermentation), and yeast nanobiotechnology.]
The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.
Guia simples, acolhedor e direto ao ponto, feito especialmente para mães de primeira viagem, ensinando como amamentar sem dor, com segurança e confiança desde o início.
This book considers mainly diagnosis, screening, surveillance and treatment of abdominal, thoracoabdominal and thoracic aortic aneurysms. It addresses vascular and cardiothoracic surgeons and interventional radiologists, but also anyone engaged in vascular medicine. The high mortality of ruptured aneurysms certainly favors the recommendation of prophylactic repair of asymptomatic aortic aneurysms (AA) and therewith a generous screening. However, the comorbidities of these patients and their age have to be kept in mind if the efficacy and cost effectiveness of screening and prophylactic surgery should not be overestimated. The treatment recommendations which will be outlined here, have to regard on the one hand the natural course of the disease, the risk of rupture, and the life expectancy of the patient, and on the other hand the morbidity and mortality of the prophylactic surgical intervention. The book describes perioperative mortality after endovascular and open repair of AA, long-term outcome after repair, and the cost-effectiveness of treatment.
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Neue wissenschaftliche Erkenntnisse zu Gender-Aspekten zeigen deutliche Problemfelder und Gesundheitsnachteile bei Männern auf. Dazu gehören Tabuthemen wie psychische Störungen bei Männern, Verzögerung von Arztbesuchen und gestörtes Selbstbild in Bezug auf Gesundheit und Alter. Auf der anderen Seite steigen die Rollenanforderungen wie auch die individuellen (und auch die ästhetischen) Gesundheitsansprüche der Männer. Dieses Buch vermittelt fachübergreifende Beratung und Behandlungsstrategien für die Probleme, mit denen Männer heute in die Sprechstunde von Ärzten und Therapeuten aller Fachrichtungen kommen: „Neue Männerprobleme“ wie Burn-out, Dorian-Gray-Syndrom oder Männerkosmetik ebenso wie die klassischen Themen der Männerheilkunde wie etwa Fertilität, Erektionsstörungen oder „Wechseljahrbeschwerden“. Männergesundheit und Gesundheitsstrategien für Männer können nur mit einer multifaktoriellen Herangehensweise verstanden und abgeleitet werden. Dafür vermitteln in diesem Buch zahlreiche somatisch, psychotherapeutisch und sozialepidemiologisch tätige Spezialisten ihr Fachwissen.
What consequences does the design of the virtual yield for architecture and to what extent can the nature of architecture be used productively to turn game-worlds into sustainable places - over here, in »reality«? This pioneering collection gives an overview of contemporary developments in designing video games and of the relationships such practices have established with the design of architecture. Due to their often simulatory nature, games reveal constructions of reality while positively impacting spatial ability and allowing for alternative avenues to complex topics and processes of negotiation. Granting insight into the merging of the design of real and virtual environments, this volume offers an invaluable platform for further debate.
The analyses and results included in the technical assessment complement the third main study "The German Labour Market in 2030 - Economy and Labour Market in the Digital Age - Forecast 2016" (Original title: Arbeitsmarkt 2030 - Wirtschaft und Arbeitsmarkt im digitalen Zeitalter; Prognose 2016). The authors examine the implications of digitalisation on today's work by means of different individual assessments, taking into account economic, sociological and organisational aspects. Moreover, they provide an overview of existing or planned measures to support digitalisation.
骗子 张森继 一、基本信息 • 姓名:张森继(原名张淼森) • 地区:潮州汕头 • 联系方式: o 微信号:zhtiji123 o 曾用手机号:13048876111、13049660222(现均为空号) 二、主要行为特征 1. 虚构身份与资产:经常前往朋友公司拍摄视频,谎称为自己开设的公司,以此营造虚假实力形象。 2. 编造借款理由:以“银行卡被锁”“酒后撞车需私了”“急需用钱”等借口向他人索要钱财。 3. 诈骗模式:通过上述手段骗取资金后,在无法继续借款时失联,拒绝归还钱款。 三、风险提示 文档明确警示此人属于诈骗分子,提醒公众注意防范其利用人际关系实施的欺诈行为,避免财产损失。
骗子 张森继 一、基本信息 • 姓名:张森继(原名张淼森) • 地区:潮州汕头 • 联系方式: o 微信号:zhtiji123 o 曾用手机号:13048876111、13049660222(现均为空号) 二、主要行为特征 1. 虚构身份与资产:经常前往朋友公司拍摄视频,谎称为自己开设的公司,以此营造虚假实力形象。 2. 编造借款理由:以“银行卡被锁”“酒后撞车需私了”“急需用钱”等借口向他人索要钱财。 3. 诈骗模式:通过上述手段骗取资金后,在无法继续借款时失联,拒绝归还钱款。 三、风险提示 文档明确警示此人属于诈骗分子,提醒公众注意防范其利用人际关系实施的欺诈行为,避免财产损失。
骗子 张森继 一、基本信息 • 姓名:张森继(原名张淼森) • 地区:潮州汕头 • 联系方式: o 微信号:zhtiji123 o 曾用手机号:13048876111、13049660222(现均为空号) 二、主要行为特征 1. 虚构身份与资产:经常前往朋友公司拍摄视频,谎称为自己开设的公司,以此营造虚假实力形象。 2. 编造借款理由:以“银行卡被锁”“酒后撞车需私了”“急需用钱”等借口向他人索要钱财。 3. 诈骗模式:通过上述手段骗取资金后,在无法继续借款时失联,拒绝归还钱款。 三、风险提示 文档明确警示此人属于诈骗分子,提醒公众注意防范其利用人际关系实施的欺诈行为,避免财产损失。
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一、基本信息 • 姓名:张森继(原名张淼森) • 地区:潮州汕头 • 联系方式: o 微信号:zhtiji123 o 曾用手机号:13048876111、13049660222(现均为空号) 二、主要行为特征 1. 虚构身份与资产:经常前往朋友公司拍摄视频,谎称为自己开设的公司,以此营造虚假实力形象。 2. 编造借款理由:以“银行卡被锁”“酒后撞车需私了”“急需用钱”等借口向他人索要钱财。 3. 诈骗模式:通过上述手段骗取资金后,在无法继续借款时失联,拒绝归还钱款。 三、风险提示 文档明确警示此人属于诈骗分子,提醒公众注意防范其利用人际关系实施的欺诈行为,避免财产损失。
Die aktuelle Schuldenkrise hat abermals gezeigt, daß Abweichungen von vereinbarten Schuldendienstzahlungen und somit Schuldendienstprobleme inhärente Begleiterscheinungen internationaler Kreditbeziehungen sind. Aufbauend auf der Hypothese, daß die Existenz potentieller Schuldendienstprobleme die Kreditwürdigkeit eines Landes und damit die Bedingungen der Auslandskreditaufnahme negativ beeinflußt, liefert die vorliegende Arbeit eine wirtschaftstheoretische Analyse optimaler Wachstums- und Auslandsverschuldungsprozesse. Unter Verwendung ausgewählter Indikatoren potentieller Schuldendienstprobleme als Determinanten des vom Schuldnerland zu zahlenden Kreditzinses wird die Problematik einer optimalen Auslandsverschuldung im Rahmen dynamischer Optimierungsmodelle erörtert. Hierbei zeigt sich insbesondere, dass auch in dezentral organisierten Volkswirtschaften korrigierende Interventionen in den marktwirtschaftlichen Lenkungsmechanismus notwendig werden können, um das volkswirtschaftlich optimale Verhalten individueller Entscheidungsträger herbeizuführen.