Elle l'aimait, elle en était aimée mais la bienséance et la mort la séparèrent de lui. Ce roman, dont Alexandre Dumas fils tira aussi un drame, est inspiré de l'existence authentique de Marie Duplessis. Merveilleusement belle et intelligente, cette courtisane fut adorée du Tout-Paris et de l'auteur lui-même. Il dut renoncer à elle, car il n'était pas assez riche. Verdi fit de ce drame un opéra sublime, La Traviata, que Franco Zeffirelli filma avec grand art. Armand et Marguerite vivent un amour immense, qui survivra à tous les obstacles et à toutes les tromperies. Le père d'Armand interdit cet amour inconvenant. Mais rien n'aura empêché le bonheur d'aimer, la virginité retrouvée, l'argent et les conventions dédaignés. L'amour véritable, c'était pour Marguerite l'espoir, le rêve et le pardon de sa vie. Tout lui fut donné, mais à quel prix ! Edition d'Antoine Livio. Cette édition du texte intégral comporte : une préface et des notes ; un commentaire ; Mademoiselle Marie Duplessis, de Jules Janin ; une bibliographie.
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Microfluidic platforms are increasingly being used for separating a wide variety of particles based on their physical and chemical properties. In the past two decades, many practical applications have been found in chemical and biological sciences, including single cell analysis, clinical diagnostics, regenerative medicine, nanomaterials synthesis, environmental monitoring, etc. In this Special Issue, we invited contributions to report state-of-the art developments in the fields of micro- and nanofluidic separation, fractionation, sorting, and purification of all classes of particles, including, but not limited to, active devices using electric, magnetic, optical, and acoustic forces; passive devices using geometries and hydrodynamic effects at the micro/nanoscale; confined and open platforms; label-based and label-free technology; and separation of bioparticles (including blood cells), circulating tumor cells, live/dead cells, exosomes, DNA, and non-bioparticles, including polymeric or inorganic micro- and nanoparticles, droplets, bubbles, etc. Practical devices that demonstrate capabilities to solve real-world problems were of particular interest.
Le Ventre de Paris [lə vɑ̃tʁ də paʁi] (1873) is the third novel in Émile Zola's twenty-volume series Les Rougon-Macquart. It is set in and around Les Halles, the enormous, busy central market of 19th Century Paris. Les Halles, rebuilt in cast iron and glass during the Second Empire was a landmark of modernity in the city, the wholesale and retail center of a thriving food industry. Le Ventre de Paris (translated into English under many variant titles but literally meaning The Belly of Paris) is Zola's first novel entirely on the working class. The protagonist is Florent, an escaped political prisoner mistakenly arrested after the French coup of 1851. He returns to his step-brother Quenu, a charcutier and his wife Lisa Quenu (formerly Macquart), with whom he finds refuge. They get him a job in the market as a fish inspector. After getting mixed up in an ineffectual socialist plot against the Empire, Florent is arrested and deported again. Although Zola had yet to hone his mastery of working-class speech and idioms displayed to such good effect in L'Assommoir, the novel conveys a powerful atmosphere of life in the great market halls and of working class suffering. There are a number of vivid descriptive passages, the most famous of which, his description of the olfactory sensations experienced upon entering a cheese shop, has become known as the "Cheese Symphony" due to its ingenious orchestral metaphors. Throughout the book, the painter Claude Lantier, a relative of the Macquarts and later the protagonist of L'Œuvre (1886) - shows up to provide a semi-authorial commentary, playing the role of chorus. It is an interesting and often powerful work, though not usually considered as being on a par with the novelist's achievements later in the Rougon-Macquart cycle. From Wikipedia (CC BY-SA).
Pakistan Current status, Increasing debt
Once more we are made aware of the fact that during the first half of the 19th century Bohemian musicians performed successfully outside their home country, in Europe as well as in the New World and in the Russian Empire, including careers in Vienna and we also learn that the readers of Viennese journals in the first place of the “Theaterzeitung” got firsthand information about the repertoire of the theatres in Prague and of theatres elsewhere. Reports and reviews about the life in the applied arts in the Bohemian lands being a rather lesser known chapter of art history allow us an insight in this field. The volume in question offers a reach source of information concerning the history of music, applied and performing arts in the Bohemian lands under Habsburg rule in the first half of the 19th century from the perspective of Viennese media.Einmal mehr wird ins Gedächtnis gerufen, dass böhmische Musiker europaweit auftraten, auch die Neue Welt und das Russische Reich bespielten, besonders aber auch an den Wiener Bühnen teils an maßgeblicher Stelle als Komponisten, Solisten oder Kapellmeister wirkten und dass, das Theaterleben betreffend, die Leserschaft der Wiener Blätter, allen voran der „Theaterzeitung“, bestens im Bilde darüber war, was in Prag und anderswo gespielt wurde.Berichte über die bildenden Künste in den böhmischen Ländern vermitteln einen Einblick in das wenig bekannte zeitgenössische Kunstgeschehen. Der vorliegende Band erschließt reichhaltige Quellen zur Theater- Musik- und Kunstgeschichte der Biedermeierzeit und schlägt ein bedeutendes Kapitel der Pressegeschichte auf. Das Wiener Vormärz-Slavica-Projekt am Institut für Kulturwissenschaften und Theatergeschichte der Österreichischen Akademie der Wissenschaften befasst sich mit der „nichtpolitischen“ Metternich‘schen Presse, indem es eine Auswertung im Hinblick auf eine spezifische Fragestellung liefert. Die vorliegende Publikation ist der dritte Teil des fünften Bandes der daraus hervorgegangenen komparatistischen Reihe betitelt: Die böhmischen Länder in den Wiener Zeitschriften und Almanachen des Vormärz (1805-1848). Tschechische nationale Wiedergeburt – Kultur- und Landeskunde von Böhmen, Mähren und Schlesien – Kulturelle Beziehungen zu Wien. Nachdem Teil I (2011) die Bereiche Belletristik und Pressewesen, Teil II (2013) die Bereiche Sprachwissenschaften – Philosophie, Ästhetik, Rhetorik – Geschichte – Bildungsinstitutionen, erschlossen haben wird in Teil III das Material zu den Künsten (Musik – Bildende Künste – Darstellende Künste) systematisch erfasst.
As soon as I entered the tents a host of menials sprang forward, some to ease me of my armour, some to offer me refreshments, some with hookahs, attar of roses (in great quart bottles), and the thousand delicacies of Eastern life. I motioned them away. ""I will wear my armour,"" said I; ""I shall go forth to-night. Carry my duty to the princess, and say I grieve that to-night I have not the time to see her.
The discovery of the negative feedback of thyroid hormones on pituitary thyroid-stimulating hormone (TSH) secretion, a classical endocrine feedback control system, has shaped diagnosis and treatment of thyroid disease for the last decades. Based on this concept, a unique diagnostic category of subclinical thyroid disorders was introduced, being defined exclusively by an abnormal TSH response in the presence of thyroid hormone concentrations within the reference range. Although this approach was able to deliver a conceptually straightforward disease definition problems surfaced in clinical practice as neither the diagnostic reference range nor the appropriate threshold for initiating substitution treatment are universally agreed upon for subclinical thyroid disorders. The situation is further aggravated by the so-called syndrome T, which comprises a substantial but heterogeneous group of L-T4 treated patients with hypothyroidism with reduced quality of life despite “normal” TSH values.A limited understanding of the physiological relationships between TSH and thyroid hormones may be a main reason for clinical difficulties in dealing with the causes of syndrome T and tailoring substitution therapy for hypothyroid patients with subclinical thyroid disorders. Feedback regulation has recently been shown to be much more complex than previously assumed. The concept of homeostatic control has also been extended to include the lesser known but equally important allostatic thyroid regulation.The latter aims at adaptive homeostasis or stability through changing setpoints and modulating structural parameters of feedback control, as may be appropriate to adapt to a vast array of conditions spanning from fetal life, aging, pregnancy, exercise, starvation, obesity, psychiatric disorders to the severe non-thyroidal illness syndrome.A better understanding of homeostatic and allostatic mechanisms, which govern the behaviour of pituitary-thyroid feedback control, is on the horizon. This promises to improve the diagnostic utility of laboratory methods, laying the foundation for personalised methods to optimise dosage and modality of substitution therapy. The emerging new world of thyroid physiology is reflected on the side of clinical medicine in a new, relational paradigm for diagnosis and treatment.Considerable progress has been made in this respect in the following key areas:• the significance of complementary information processing structures within the feedback loop, in particular ultrashort feedback of TSH on its own secretion and the action of a TSH-T3 shunt unburdening the thyroid from T4 synthesis in imminent thyroid failure,• the unravelling of spatio-temporal dynamics of hormone concentrations ranging from ultradian to circannual rhythms and including hysteresis effects,• the emergence of “non-canonical” mechanisms of thyroid hormone signalling beyond transcriptional control of gene expression,• the physiological actions of thyronine metabolites, which have been previously regarded as biologically inactive, such as thyronamines and iodothyroacetates,• the characterisation of distinct patterns in the adaptive processes to stress and strain and their conclusive explanation through reactions to type 1 and type 2 allostatic load.This collective volume contains the contributions to the Research Topic “Homeostasis and Allostasis of Thyroid Function”, which was originally published by the journal Frontiers in Endocrinology. Authored by an international team of experts from three continents ,the book provides a comprehensive overview on thyroid control from recent research in basic, computational and clinical thyroidology. Many aspects addressed here can be expected to stimulate future research. A more comprehensive view and better integration of in-vitro, in-silico and in-vivo investigations will be invaluable in paving the way to this new world of thyroidology.
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The Special Issue contains ten research papers, three of which review papers. It is a miscellaneous composition encompassing several applications where metal oxides play a key role. Some papers also give insights into novel synthesis methods and processes aiming to reduce negative environmental impacts and increase materials and process efficiency, thus also covering a broader concern of sustainability issues. The topics covered in this issues are: transparent conductive oxides, ceramic composites for tool applications, oxides nanoparticles for A-TIG welding, critical raw materials saving, metallurgical waste treatment, oxides for high temperature applications, nanostructured oxides and composites for gas sensing and desulfuration, and metal oxides sorbents for CO2 capture.
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Expertinnen und Experten zeigen in Originalbeitrgen, wie an verschiedenen Stellen von der Grundschule bis zur Wahl einer weiteren Ausbildung nach der Grundausbildung Bildungsverlufe beeinflusst werden, beispielsweise durch die Frderung von verhaltensaufflligen Kindern in der Grundstufe, durch die Gestaltung von Selektionsverfahren in die Sekundarstufe I oder durch die Organisation der Berufsorientierung vor der Sekundarstufe II. Der Sammelband vereint neue theoretische Anstze und empirische Befunde, die auf aktuellen, lngsschnittlichen Datenstzen beruhen. Der InhaltDiachrone Bildungsverlufe Übergnge in der Schule Übergnge in der BerufsbildungDie ZielgruppenForschende, Dozierende und Studierende der Erziehungswissenschaften, Lehrkraftbildung, Psychologie, Soziologie und ÖkonomieMitarbeitende von Bildungsverwaltungen, Berufsberaterinnen und Berufsberater, Coaches, Schulleitungen, Lehrpersonen an Grund- und Berufsfachschulen, BildungsverantwortlicheDie Herausgeber Prof. Dr. Markus P. Neuenschwander ist Professor fr Pdagogische Psychologie und leitet das Zentrum Lernen und Sozialisation der Pdagogischen Hochschule der Fachhochschule Nordwestschweiz und ist Mitglied des Instituts fr Bildungswissenschaften der Universitt Basel. Dr. Christof Ngele ist Projektleiter und wissenschaftlicher Mitarbeiter am Zentrum Lernen und Sozialisation der Pdagogischen Hochschule der Fachhochschule Nordwestschweiz.
This volume presents several case studies highlighting the latest findings in Industry 4.0 projects utilizing S-BPM features. Their potential is explored in detail, while the limits of engineering a company from a communication-centred perspective are also discussed. After a general introduction and an overview of the book in chapter 1, chapter 2 starts by condensing the industrial challenges driven by the German Industry 4.0 trend to form a concrete vision for future production industries. Subsequently, chapter 3 introduces the basic concepts of S-BPM and its capabilities, in particular for supporting the restructuring of processes. The next three chapters then present various case studies, e.g. at an SME offering the production of atypical, unique and special purpose machinery, equipment and technologically complex units particularly useful in the automotive and electronic industries; and at a further SME producing highly-customized floor cleaning machines. Rounding out the coverage, the last two chapters summarize the achievements and lessons learned with regard to the road ahead. Overall, the book provides a realistic portrait of the status quo based on current findings, and outlines the future activities to be pursued in order to establish stakeholder-centred digital production systems. As such, developers, educators, and practitioners will find both the conceptual background and results from the field reflecting the state-of-the-art in vertical and horizontal process integration.
The human intestine is home of an almost inconceivable large number of microorganisms. The human gut microbiota can therefore be pictured as an organ placed within a host organism. The human gut microbiome, which in total may contain >100 times the number of genes present in our genome, endows us with functional features that we did not have to evolve ourselves. It is recognized that intestinal microbiota plays an important role in human health and disease. In fact, gut bacteria other than metabolize dietary components, may play complex roles such as modulation of the immune system and in reduction of gut infections. Variations in the presence and/or abundance of certain components of the intestinal microbiota have repeatedly been observed in patients that suffer from atopic diseases, inflammatory bowel disease, Crohn disease, ulcerative colitis, infectious colitis, colon cancer and diabetes. In this context, bifidobacteria represent one of the most common bacterial members of the human gut microbiota. Bifidobacteria are anaerobic, Gram-positive, irregular or branched rod-shaped bacteria that are commonly found in the gastro-intestinal tracts (GIT) of humans, especially during the first stages of life and most animal and insects. Bifidobacterial fluctuations seem directly associated with health effects and for these reasons they are being exploited as health-promoting or probiotic bacteria. However, despite the extensive commercial exploitation of bifidobacteria as probiotic bacteria, little is known about their impact or dependency on other members of the human gut microbiota or on their host. Genome analyses have highlighted the existence of gene repertoires encoding products that are responsible for the adaptation of bifidobacteria to the human intestine and intense research efforts at international level are ongoing to understand the molecular details of these interactions. Specifically, the molecular interactions that are presumed to exist between bifidobacteria and the human host, as well as interactions between different residents of intestinal microbiota are the main topic of bifidobacterial research communities.
Beggars and begging were ubiquitous features of pre-Famine Irish society, yet have gone largely unexamined by historians. This book explores at length for the first time the complex cultures of mendicancy, as well as how wider societal perceptions of and responses to begging were framed by social class, gender and religion. The study breaks new ground in exploring the challenges inherent in defining and measuring begging and alms-giving in pre-Famine Ireland, as well as the disparate ways in which mendicants were perceived by contemporaries. A discussion of the evolving role of parish vestries in the life of pre-Famine communities facilitates an examination of corporate responses to beggary, while a comprehensive analysis of the mendicity society movement, which flourished throughout Ireland in the three decades following 1815, highlights the significance of charitable societies and associational culture in responding to the perceived threat of mendicancy. The instance of the mendicity societies illustrates the extent to which Irish commentators and social reformers were influenced by prevailing theories and practices in the transatlantic world regarding the management of the poor and deviant. Drawing on a wide range of sources previously unused for the study of poverty and welfare, this book makes an important contribution to modern Irish social and ecclesiastical history.This book is made open access as part of the Knowledge Unlatched KU Select 2018: HSS Frontlist Books
Foundling boy's autobiography. Involves travel with patent medicine show.
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Version 1 of the Isilang project Dreampaper.