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The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic research may be more clinically translatable than other omics approaches, since metabolites are closely related to the phenotype and the metabolome is sensitive to many factors. Metabolomics seems promising to identify key metabolic pathways characterizing features of pathological and physiological states. Thus, knowing that tumor metabolism markedly differs from the metabolism of normal cells, the use of metabolomics is ideally suited for biomarker research. Some works have already focused on the application of metabolomic approaches to different cancers, namely lung, breast and liver, using urine, exhaled breath and blood. In this Special Issue we contribute to a more complete understanding of cancer disease using metabolomics approaches.

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In Okinawa, the southernmost prefecture of Japan, “ecotourism” promises to provide employment for a dwindling population of rural youth while preserving the natural environment and bolstering regional pride. Footprints in Paradise centers on how Okinawans’ sense of place is transforming rapidly, along with language, landscapes, cultural traditions, and wildlife: from marginalized and exoticized island phenomena into global heritage resources worth cherishing by insiders and outsiders. Footprints in Paradise is intended for readers interested in the anthropology of US-Japan-Okinawa relations, tourism and island environments, the politics of ecological sustainability, and the shifting ethics of human-animal relationships in the early twenty-first century.

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People interpret their biographies in order to give them a subjective meaning. In institutionalized biographies, biographies also become normatively charged patterns of progress. They reflect the tension between life courses and culturally and socially shaped generalized patterns of life-style. The volume collects selected peer-reviewed contributions on this topic.

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Universities are social universes in their own right. They are the site of multiple, complex and diverse social relations, identities, communities, knowledges and practices. At the heart of this book are people enrolling at university for the first time and entering into the broad variety of social relations and contexts entailed in their ‘coming to know’ at, of and through university.By recasting ‘the transition to university’ as simultaneously and necessarily entailing a transition of university — indeed universities — and of their many and varied constitutive relations, structures and practices, the contributors to this book seek to reconceptualise the ‘first-year experience’ in terms of multiple and dynamic processes of dialogue and exchange amongst all participants. They interrogate taken-for-granted understandings of what ‘the university’ is, and consider what universities might yet become.

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With a focus on ten notable Australians, including Nobel Laureates Professor Barry Marshall and Professor Brian Schmidt, former Chief Scientist, Professor Ian Chubb, and Parliamentarian, the Honourable Linda Burney, The Power of Conferences explores the deep and lasting impact of conferences on the development and success of Australian luminaries.Each chapter features a reflection from a leader in Australian academia, politics, or community service, on the significant effects conferences have had on their personal and professional achievements.From chance encounters that result in the cultivation of new networks and collaborations to innovation and research breakthroughs, these leaders describe the conferences that have enabled them and others to go on to create real and lasting social change.

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Die Bibliothek und das Schrifttum Guido Adlers (1855–1941), des prominentesten Vertreters der Musikwissenschaft der Universität Wien, wurde von den Nationalsozialisten unter reger Beteiligung von Mitarbeitern der Universität Wien geraubt und später nur zum Teil zurückgegeben. Im Rahmen der NS-Provenienzforschung an der Universitätsbibliothek Wien konnten Restbestände der Bibliothek Guido Adlers festgestellt werden. Auch ein Nachlassfragment wurde als bedenklich identifiziert und mit den Buchbeständen 2012/13 restituiert.

Karl Kiesewetter

PD-US

Waterman Engineers Australia has decades of experience in water treatment, wastewater treatment, drinking water purification, Water filtration plants, reverse osmosis systems, desalination plants, Ultrafiltration, Microfiltration, Nanofiltration, effluent recycling, zero liquid discharge system, Waste Incinerator for solid liquid waste management from concept to commissioning. We have been doing water treatment plants turnkey projects in textile, mining, pharmaceuticals (including pharmaceutical-grade water), refineries, chemicals, petrochemicals, oil and gas, dyestuff, beverage industries, fruit juice industries, and energy drink industries for decades. We have completed turnkey projects for the pharmaceutical industry using electro-deionization (EDI systems) for pharma-grade water and injectable water.

The Eye Center, P.A.

Dry eye is a common condition that occurs when the eye does not produce enough tears, or the tears evaporate too quickly. It can cause symptoms such as burning, stinging, redness, and blurred vision.

Lamiply PUNE

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Antimicrobial peptides and complement are distinct components of the innate immune defence. While antimicrobial peptides, after cleavage of a preproprotein, have the ability to insert directly in non host membranes, complement requires a sequential enzymatic activation in the fluid phase in order to produce a transmembrane membrane attack complex. Its insertion is controlled by membrane bound regulators. Deficiencies are described for both effectors and relate to increased susceptibility of infection. In addition, however, antimicrobial peptides and complement each influence the activity of inflammatory cells as recent data in the respective research areas shows. This series of articles draws together for the entities of antimicrobial peptides and complement a balance of contributions in the areas of evolution, roles, functions and preclinical applications. By comparing and contrasting antimicrobial peptides and complement, greater cross-disciplinary appreciation will be derived for their individual and overlapping spectra of activity, circumstances of activation and their general ability to more completely inform the inflammatory and cellular response.

Rose Wilder Lane

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PD-US

Supreme Auto Detailing

Supreme Auto Detailing offers top-quality car detailing services in East Providence RI that help your vehicle stay clean and well-maintained. This company has various services, including full interior cleaning, exterior wash and wax, and engine cleaning. This company offers packages to fit diverse needs, ensuring each service is designed to enhance your car's shine and appearance.

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The dissertation investigates in which way the juvenile penal law allows for victim rights. This ques-tion is treated dogmatically and discussed in the lights of an empirical survey made specifically for this dissertation.Der Gesetzgeber hat die Stellung des Verletzten im Strafverfahren in den letzten Jahrzehnten erheblich verändert. Die dem Verletzten nach und nach eingeräumten Informations-, Mitwirkungs- und Schutzrechte „stören“ das klassische Gegenüber von strafverfolgendem Staat und Angeklagten. In wichtigen Bereichen des Strafverfahrens muss daher eine neue Balance hergestellt werden. Das ist besonders prekär im vom Erziehungsgedanken beherrschten Jugendstrafverfahren. Die Arbeit untersucht, inwiefern die Besonderheiten des Jugendstrafverfahrens eine Berücksichtigung von Opferrechten zulassen. Im ersten Teil der Arbeit werden die dogmatischen Grundlagen einer Einbeziehung des Verletzten in das Jugendstrafverfahren dargestellt und die einzelnen Verletztenrechte ausführlich erörtert. Über die bloß theoretische Diskussion hinaus, wird im zweiten Teil der Arbeit der Konflikt zwischen den Verfahrensrechten des Verletzten und der erzieherischen Ausrichtung des Jugendstrafverfahrens empirisch beleuchtet. Zu diesem Zweck wurden Jugendrichter, Jugendstaatsanwälte und Strafverteidiger zu ihren Einstellungen, ihren Einschätzungen und ihrer praktischen Handhabung befragt.

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Eugenia Smagina (Евгeния Б. Смaгина) first published her grammar of the Old Nubian language in 1986 in Russian. For more than thirty years the work has remained untranslated, even though the late Gerald M. Browne affirmed that “this lucid, well-argued presentation should be available to all Nubiologists and ought therefore be translated into a western language.”Slavicist José Andrés Alonso de la Fuente has prepared a first English translation of this concise but indispensable work, which forms a necessary counterpart to Browne’s classic Old Nubian Grammar. The grammar is divided into sections on script, lexicon, morphology, and syntax, and is followed by the analysis of a sample text, known as The Miracle of St. Mēnas.Smagina’s The Old Nubian Language provides an excellent first introduction into the grammar of this medieval Nilo-Saharan language.

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Click Here---> http://bit.ly/2lepCOc <---Get complete detail on DEV-402 exam guide to crack Platform App Builder. You can collect all information on DEV-402 tutorial, practice test, books, study material, exam questions, and syllabus. Firm your knowledge on Platform App Builder and get ready to crack DEV-402 certification. Explore all information on DEV-402 exam with number of questions, passing percentage and time duration to complete test.

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Phoebe Ayers

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How Wikipedia Worksis a guide to understanding and using Wikipedia, for readers with a basic understanding of the project. Wikipedia, the free encyclopedia, is the largest and most popular reference web- site in the world. Wikipedia is also unique: This encyclopedia is written by everyone and can be read by anyone. This book is written for readers, current editors, potential contributors, and anyone else interested in Wikipedia. The book describes what kind of writing Wikipedia includes, how Wikipedia works behind the scenes, and how to get involved. We cover all aspects of participating in Wikipedia, from reading the site to editing articles to navigating the sites community and governance. Wikipedia is made up of people just like you: students, professors, and everyday experts and fans. With about 10,000 articles added to Wikipedia each week, there are plenty of opportunities to join this global community.How Wikipedia Worksexplains how you can make the Webs go-to source for information even better. After reading, feel free to contact the authors or submit errata.

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Shweta

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Anna Bowman Dodd

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Roman law is widely considered to be the foundation of European legal culture and an inherent source of unity within European law. Roman Law and the Idea of Europe explores the emergence of this idea of Roman law as an idealized shared heritage, tracing its origins among exiled German scholars in Britain during the Nazi regime. The book follows the spread and influence of these ideas in Europe after the war as part of the larger enthusiasm for European unity. It argues that the rise of the importance of Roman law was a reaction against the crisis of jurisprudence in the face of Nazi ideas of racial and ultranationalistic law, leading to the establishment of the idea of Europe founded on shared legal principles.&#xD;&#xD;With contributions from leading academics in the field as well as established younger scholars, this volume will be of immense interests to anyone studying intellectual history, legal history, political history and Roman law in the context of Europe.