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The German reunification in 1989/90 is paradigmatic for fundamental geopolitical changes, in the context of a change of the entire legal system. Further well-known examples of the State’s national desire for reformations with respect to legal principles are the great reform of the penal system in 1975, the reform of the law of obligations in 2002 and the fundamental reorganization of the law with respect to illiquid debtors. The Koreans are not only interested in the Germans’ experience of the last quarter of a century because of legal-historical reasons, but also in particular because of the possible case of a Korean reunification. The present volume contains the contributions to the 4th symposium of the Faculty of Law of the Georg-August-Universität Göttingen and the Yonsei Law School (Seoul), which was held in Göttingen in February 2015.

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Rheumatoid Arthritis (RA) is a chronic inflammatory disease leading to joint inflammation and destruction. Treatment of RA includes the use of conventional (cs), biologic (b) disease-modifying anti-rheumatic drugs (DMARDs), and oral or intraarticular (IA) glucocorticoids (GCs). All different classes of drugs have shown to halt disease progression in clinical studies. In real life, a physician has more options than just adding or switching to a new ts/bDMARD if any kind of DMARDs has failed. They can modify or optimize the therapy with concomitant csDMARDs, and oral or IA-GC can be added to the treatment regimen. The EULAR states that therapeutic adjustment including the "optimization of csDMARDs dose or route of administration or intra-articular injections of GCs" is recommended. Thus, a new therapeutic agent can be embedded in a whole strategy with parallel optimization of the csDMARD and GC treatment. The idea of treating to target (T2T) for the treatment of RA patients has been around since the late 1990s. Many clinical studies (Ticora, BsSt, Camera) have demonstrated the superiority of a T2T approach. When I talk to physicians, I understand that most of them only rarely inject joints with GC. Therefore, I would like to create an issue on the T2T approach in reality including primary data, reviews, and real-life data demonstrating the general opinion and execution of T2T in treating RA.

Joel Tyler Headley

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