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Dutch literature - Flemish literature; HistoryKlassieke mythologie was een geliefd onderwerp bij de rederijkers van de zestiende eeuw. Deze ‘fabulen’ werden bewerkt tot spelen van zinne waarin herkenbare liefdeskwesties aan de orde kwamen. Er zijn negen van deze zogeheten mythologisch- amoureuze spelen overgeleverd, geschreven en opgevoerd vanaf het einde van de vijftiende eeuw. De teksten maken duidelijk hoe de omgang met klassieke mythologie veranderde in de periode die de overgang vormt van middeleeuwen naar moderne tijd. Deze studie gaat in op de verhouding tot de oorspronkelijke teksten, op de dramaturgie en opvoering van de spelen en op de overlevering in handschrift en druk. De mythologie, heidens en fictioneel van aard, bood ruimte om te experimenteren met de uitbeelding van erotiek en emoties, terwijl de dramaturgie een didactisch kader vormde dat tegemoet kwam aan de sociale en ethische behoeften van die tijd. De mythologisch-amoureuze spelen droegen daarmee bij aan de introductie, verspreiding en acceptatie van antieke mythologie in de volkstalige cultuur en aan de ontwikkeling van een effectieve liefdesdidactiek.

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Redmond, James

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Available Open Access under CC-BY-NC licence. Health literacy addresses a range of social dimensions of health, including knowledge, navigation and communication, as well as individual and organizational skills for accessing, understanding, evaluating and using information. Particularly over the past decade, health literacy has globally become a major public health concern as an asset for promoting health, wellbeing and sustainable development.

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Matrix metalloproteinases (MMPs) are members of an enzyme family and are critical for maintaining tissue allostasis. MMPs can catalyze normal turnover of the extracellular matrix (ECM) together with other metalloproteinases such as ADAM (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) families. MMP activity is also regulated by a group of endogenous proteins called tissue inhibitor of metalloproteinases (TIMPs). All these proteins have a pivotal role involving ECM remodelling in normal physiological processes such as wound healing, embryogenesis, angiogenesis, bone remodelling, immunity, and the female reproductive cycle. An imbalance in the expression or activity of MMPs can also have important consequences in diseases such as cancer, cardiovascular disease, peripheral vascular disease, chronic leg ulcers, and multiple sclerosis. In recent years, MMPs have been found to play an important role in the field of precision medicine, as they may serve as biomarkers that may predict an individual’s disease predisposition, state, or progression. MMPs are also thought to be a sensible target for molecular therapy. The aim of this Special Issue is to explore the most recent findings in this field that may have an impact in healthcare systems.

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