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In recognizing that new teachers often feel disempowered by the subject expertise they bring into teaching, this book not only covers the training standards for NQTs and the Induction Standards, but takes the reader beyond this by fully exploring issues relating to subject knowledge in learning to teach. Divided into three sections the book covers: framing the subject - defining subject knowledge and focusing on questions about science as a school subject teaching the subject - looking at pedagogical, curricular and pupil knowledge science within the professional community - focusing on the place of science within the wider curriculum and the teaching community. This refreshing new book provides stimulating assistance to subject specialists, from new teachers of science in the early years of professional development to those on a PGCE course or in their induction year. It is also suitable for subject leaders with mentor responsibilities and Advanced Skills Teachers undertaking specialist inset and teaching support.

HP

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Nonequilibrium statistical mechanics has a long history featuring diverse aspects. It has been a major research field in physics and will remain so in the future. Even regarding the concept of entropy, there exists a longstanding problem concerning its definition for a system in a state far from equilibrium. In this Special Issue, we offered the possibility to discuss and present up-to-date problems that were not necessarily restricted to statistical mechanics. Theoretical and experimental papers are both presented, in addition to unifying research works. As the entropy itself is the central element of nonequilibrium processes, papers discuss various formulations of the second law and its consequences. In this Special Issue, recent progress in kinetic approaches to hydrodynamics, rational extended thermodynamics, entropy in a strongly nonequilibrium stationary state, and related topics are reported as both review articles as well as original research works.

Naman Gupta

Snippets of all GST Notifications since inception

Hearing Aid Price In Pakistan

Hearing loss can significantly impact an individual's quality of life, making it essential to invest in hearing aid price in pakistan or ear machines. In Pakistan, there is a range of options available to cater to diverse needs and budgets. This article delves into the factors affecting hearing aid and ear machine prices in Pakistan, helping you make informed decisions about your auditory health.

ravi sharma

Reks

DumpsBase

Real Exam Dumps

If you wish to pass User Experience Designer Salesforce Certified User Experience Designer certification exam on the first attempt, you can choose real Salesforce User Experience Designer Exam Dumps V9.02 as the preparation materials. If you are searching for the real User Experience Designer exam dumps with verified questions and answers then you ought to get the DumpsBase User Experience Designer dumps to prepare and pass the Salesforce Certified User Experience Designer certification exam with brilliant final results. You can be here to read User Experience Designer free dumps questions online.

Aggiler

Many beginners believe that by overloading their designs, they will catch the attention of users, but this is not the case with the Best graphic designing company in India. Excessive graphics, type, and colors will turn away your users rather than capture their attention, whereas simplicity will keep them on your website for a longer period.

Standing out in the ever-evolving world of online entertainment, HuraWatch is recognized as a premier streaming website. It boasts an extensive collection of movies and TV shows that cater to a wide range of tastes and preferences. Whether you're a fan of action-packed thrillers, heartwarming dramas, or hilarious comedies, it has content to suit all viewers.

lenovo

Eziokwu C. Emmanuel

We know that a large number of problems in differential equations can be reduced to finding the solution x to an equation of the form Tx=y. The operator T maps a subset of a Banach space X into another Banach space Y and y is a known element of Y. If y=0 and Tx=Ux−x, for another operator U, the equation Tx=y is equivalent to the equation Ux=x. Naturally, to solve Ux=x, we must assume that the range R (U) and the domain D (U) have points in common. Points x for which Ux=x are called fixed points of the operator U. In this work, we state the main fixed-point theorems that are most widely used in the field of differential equations. These are the Banach contraction principle, the Schauder–Tychonoff theorem, and the Leray–Schauder theorem. We will only prove the first theorem and then proceed..

WINDOWS

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Dr. Riza Kadilar is one such visionary who has seamlessly traversed the spheres of banking, training, coaching, and mentoring. With a background deeply rooted in banking, he’s been a senior banking executive as an approved person by regulatory authorities in the U.K., the Netherlands, France, and Turkey.

Wisdom Mart

Online GRE Coaching classes give a superior edge by saving time to practice and learn more.

Harold Abelson

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Wherever you go‚ whatever you say, write, photograph, or buy‚ whatever prescriptions you take, or ATM withdrawals you make you are generating information. That information can be captured, digitized, retrieved, and copied ‚ anywhere on Earth, instantly. Sophisticated computers can increasingly uncover meaning in those digital traces‚ understanding, anticipating, and influencing you as never before. Is this utopia? Or the dawning of a 1984/Brave New World horror world? Whatever you call it, it’s happening. What kind of world are we creating? What will it be like to live there? Blown to Bits offers powerful and controversial answers to these questions‚ and give you the knowledge you need to help shape your own digital future, not let others do it for you. Building on their pioneering joint MIT/Harvard course, the authors reveal how the digital revolution is changing everything, in ways that are stunning even the most informed experts. You’ll discover ten paradoxical truths about digital data, and learn how those truths are overturning centuries-old assumptions about privacy, identity, and personal control. You’ll view the indelible digital footprints you’re making when you search Google, send emails and text messages‚ write Microsoft Word documents‚ download MP3s‚ make cellphone calls‚ post blog entries‚ pay highway tolls‚ use your supermarket discount card. And you’ll see how others could be following those footprints, in ways you never thought about, and might not like. Writing in plain English, the authors illuminate the myriad implications of the digital revolution, answering the questions you’ve wondered about‚ or ought to wonder about. Who owns all that data about you? What do they owe you? How private is your medical information? Is it possible to send a truly secure message? Who can you trust for accurate information when traditional media is replaced by thousands of unfiltered Internet sources? Along the way, they reveal the decisions governments and corporations are making right now that will shape your future‚ and show how to have your say in those decisions. Because you have an enormous stake in the outcome. We all do. How the Digital Revolution Is Transforming Your World More Profoundly Than You Ever Imagined > Who’s watching you, what do they know about you, and what will they do with that knowledge? > Is it time to say goodbye forever to privacy and personal identity? > What kind of world are we creating‚ and what will it be like to live there? Blown to Bits is available at Amazon.com, Borders, Barnes and Noble, local booksellers, and, as a PDF for download, here.

Samuel Fleischacker

chandan

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Beton Makaya_OA

Public

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Frank L. (Frank Lucius) Packard

PD-US

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The immune system detects "danger" through a series of what we call pathogen-associated molecular patterns (PAMPs) or damage-associated molecular pattern molecules (DAMPs), working in concert with both positive and negative signals derived from other tissues. PAMPs are molecules associated with groups of pathogens that are small molecular motifs conserved within a class of microbes. They are recognized by Toll-like receptors (TLRs) and other pattern recognition receptors. A vast array of different types of molecules can serve as PAMPs, including glycans and glycoconjugates. Bacterial lipopolysaccharides (LPSs), endotoxins found on the cell membranes of Gram-negative bacteria, are considered to be the prototypical class of PAMPs. LPSs are specifically recognized by TLR4, a recognition receptor of the innate immune system. Other PAMPs include bacterial flagellin (recognized by TLR5), lipoteichoic acid from Gram-positive bacteria, peptidoglycan, and nucleic acid variants normally associated with viruses, such as double-stranded RNA, recognized by TLR3 or unmethylated CpG motifs, recognized by TLR9. DAMPs, also known as alarmins, are molecules released by stressed cells undergoing necrosis that act as endogenous danger signals to promote and exacerbate the immune and inflammatory response. DAMPs vary greatly depending on the type of cell (epithelial, mesenchymal, etc.) and injured tissue. Some endogenous danger signals include heat-shock proteins, HMGB1 (high-mobility group box 1), reactive oxygen intermediates, extracellular matrix breakdown products such as hyaluronan fragments, neuromediators, and cytokines like the interferons (IFNs). Non-protein DAMPs include ATP, uric acid, heparin sulfate, and DNA. Furthermore, accumulating evidence supports correlation between alarmins and changes in the microbiome. Increased serum or plasma levels of these DAMPs have been associated with many inflammatory diseases, including gastric and intestinal inflammatory diseases, graft-versus-host disease (GVHD), sepsis and multiple organ failure, allergies particularly in the lungs, atherosclerosis, age-associated insulin resistance, arthritis, lupus, neuro-inflammation/degeneration and more recently in tumors, which is particularly interesting with the emergence of immunotherapies. Therapeutic strategies are being developed to modulate the expression of these DAMPs for the treatment of these diseases.A vast number of reviews have already been published in this area; thus, in an effort to not duplicate what has already been written, we will focus on recent discoveries particularly in disease models that are epidemic in Western society: intestinal chronic inflammatory diseases including GVHD and its relationship with the microbiome, chronic infectious diseases, allergies, autoimmune diseases, neuroinflammation and cancers. We will also focus on the basic cellular roles of macrophages, T cells and B cells. This research topic brings together sixteen articles that provide novel insights into the mechanisms of action of DAMPS/alarmins and their regulation and subsequent immunologically driven responses.

Prateek Sharma

Computer Science and Engg.

William K. (William Kurtz) Wimsatt (editor)

PD-US

Windows User