This open access book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET) for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis. In turn, the second part addresses evidence-based PET in oncology, providing a broad overview of its use for different types of tumours. The remaining sections are focused on the use of PET in cardiology, in infectious and inflammatory diseases, and in neurology, respectively. Given its scope and the wealth of information it provides, the book will be an invaluable tool for clinicians with various specialties, as well as international scientific societies interested to the recent evidence-based data about PET.
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Arrest chemokines are a small group of chemokines that promote leukocyte arrest from rolling by triggering rapid integrin activation. Arrest chemokines have been described for neutrophils, monocytes, eosinophils, naïve lymphocytes and effector memory T cells. Most arrest chemokines are immobilized on the endothelial surface by binding to heparin sulfate proteoglycans. Whether soluble chemokines can promote integrin activation and arrest is controversial (Alon-Gerszten). Many aspects of the signaling pathway from the GPCR chemokine receptor to integrin activation are the subject of active investigation. Leukocyte adhesion deficiency III is a human disease in which chemokine-triggered integrin activation is defective because of a mutation in the cytoskeletal protein kindlin-3. About 10 different such mutations have been described. The defects seen in patients with LAD-III elucidate the importance of rapid integrin activation for host defense in humans. We welcome reports that help clarifying this crucial first step in the process of leukocyte transendothelial migration.
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Bến tre nằm ở hạ lưu sông Mekong, giáp với biển Đông, với mạng lưới sông ngòi chằng chịt. Bến Tre rất thuận lợi về giao thông đường thủy, nguồn thủy sản phong phú, nước tưới cho cây trồng ít gặp khó khăn.
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"Empire and Catastrophe examines natural and anthropogenic disasters during the years of decolonization in Algeria, Morocco, and France, and explores the ways in which environmental catastrophes both shaped and were shaped by struggles over the dissolution of France’s empire in North Africa. Four disasters make up the core of the book: the 1954 earthquake in Algeria’s Chélif Valley, just weeks before the onset of the Algerian Revolution; a mass poisoning in Morocco in 1959 caused by toxic substances from an American military base; the 1959 Malpasset dam collapse in Fréjus, France, which devastated the Algerian immigrant community in the town but which was blamed on Algerian sabotage; and the 1960 earthquake in Agadir, Morocco, which set off a public relations war between the United States, France, and the Soviet Union, and which ignited a Moroccan national debate over modernity, identity, architecture, and urban planning. Empire and Catastrophe is the first book-length study of environmental disasters during the decolonization of the French empire. Interrogating distinctions between agent and environment and between political and environmental violence, through the lenses of state archives and through the remembered experiences and literary representations of disaster survivors, this book argues for the integration of environmental events into narratives of political and cultural decolonization. Empire and Catastrophe will be sought after by environmental historians and North Africa area studies specialists as well as historians of France and French imperialism. Written in engaging prose, the book will appeal to the broader public’s interest in natural disasters, and will become required reading for undergraduates in courses on natural disasters in world history."
Para establecer una muerte por negligencia en un accidente automovilístico, reúna pruebas como informes policiales, declaraciones de testigos y registros médicos. En este PDF, explicamos algunos pasos que puede tomar la familia de la víctima en caso de negligencia de otros. Haga clic aquí para obtener más información o contratar a nuestro abogado experimentado en caso de cualquier accidente.
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