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This book brings together new developments in the area of strain-engineered MOSFETs using high-mibility substrates such as SIGe, strained-Si, germanium-on-insulator and III-V semiconductors into a single text which will cover the materials aspects, principles, and design of advanced devices, their fabrication and applications. The book presents a full TCAD methodology for strain-engineering in Si CMOS technology involving data flow from process simulation to systematic process variability simulation and generation of SPICE process compact models for manufacturing for yield optimization.This book is made open access as part of the Knowledge Unlatched KU Select 2018: STEM Backlist Books
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Zinc-dependent matrix metalloproteinases (MMPs) belong to metzincins that comprise not only 23 human MMPs but also other metalloproteinases, such as 21 human ADAMs (a disintegrin and metalloproteinase domain) and 19 secreted ADAMTSs (a disintegrin and metalloproteinase thrombospondin domain). The many setbacks from the clinical trials of broad-spectrum MMP inhibitors for cancer indications in the late 1990s emphasized the extreme complexity of the participation of these proteolytic enzymes in biology. This editorial mini-review summarizes the Special Issue, which includes four review articles and 10 original articles that highlight the versatile roles of MMPs, ADAMs, and ADAMTSs, in normal physiology as well as in neoplastic and destructive processes in tissue. In addition, we briefly discuss the unambiguous involvement of MMPs in wound healing.
The volume reproduces the documentary path of the exhibition Florence in the war 1940-1944 promoted by the Historical Institute of the Resistance in Tuscany on the occasion of the 70th anniversary of the Resistance and Liberation. Introductory contributions illustrate the work in progress who accompanied the exhibition project and intend to guide the reader through a series of historiographical questions at the center of the exhibition: the centrality of the 1940-1943 phase, which has hitherto remained in the background, the economic transformations, the knots of consent and social control, the characters of the German occupation, the role of the Church and the complex plot of the Florentine Resistance. The aim of the research was to closely investigate the impact of the war on the population of a large urban area, trying to highlight its specificity and connections with the national framework.
A quarter century period of the 3D printing technology development affords ground for speaking about new realities or the formation of a new technological system of digital manufacture and partnership. The up-to-date 3D printing is at the top of its own overrated expectations. So the development of scalable, high-speed methods of the material 3D printing aimed to increase the productivity and operating volume of the 3D printing machines requires new original decisions. It is necessary to study the 3D printing applicability for manufacturing of the materials with multilevel hierarchical functionality on nano-, micro- and meso-scales that can find applications for medical, aerospace and/or automotive industries. Some of the above-mentioned problems and new trends are considered in this book.
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Nature Reviews Microbiology, doi:10.1038/s41579-018-0118-9
Los trabajos aquí reunidos reflejan el resultado de las comunicaciones y conferencias presentadas en el Coloquio Internacional Sobre el pensamiento de Maurice Merleau-Ponty desarrollado durante los días 6 y 7 de diciembre de 2016 en la FaHCE-UNLP. En él se pusieron a consideración y debate interpretaciones sobre algunos tópicos fundamentales de la obra del pensador francés, tales como las nociones de cuerpo, carne, quiasmo y naturaleza. Se revisaron relaciones distintivas en sus reflexiones poniendo el foco en el arte, en la historicidad, en la pintura y en la ciencia, así como algunos cruces posibles con otros pensamientos como los de Husserl, Heidegger, Rancière, Ricoeur, o el de los estudios de género.
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This book highlights the ethical issues and dilemmas that arise in the practice of public health. It is also a tool to support instruction, debate, and dialogue regarding public health ethics. Although the practice of public health has always included consideration of ethical issues, the field of public health ethics as a discipline is a relatively new and emerging area. There are few practical training resources for public health practitioners, especially resources which include discussion of realistic cases which are likely to arise in the practice of public health. This work discusses these issues on a case to case basis and helps create awareness and understanding of the ethics of public health care. The main audience for the casebook is public health practitioners, including front-line workers, field epidemiology trainers and trainees, managers, planners, and decision makers who have an interest in learning about how to integrate ethical analysis into their day to day public health practice. The casebook is also useful to schools of public health and public health students as well as to academic ethicists who can use the book to teach public health ethics and distinguish it from clinical and research ethics.
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