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Highly innovative and theoretically incisive, Two Lenins is the first book-length anthropological examination of how social reality can be organized around different yet concurrent ideas of time. Nikolai Ssorin-Chaikov grounds his theoretical exploration in fascinating ethnographic and historical material on two Lenins: the first is the famed Soviet leader of the early twentieth century, and the second is a Siberian Evenki hunter—nicknamed “Lenin”—who experienced the collapse of the USSR during the 1990s. Through their intertwined stories, Ssorin-Chaikov unveils new dimensions of ethnographic reality by multiplying our notions of time.Ssorin-Chaikov examines Vladimir Lenin at the height of his reign in 1920s Soviet Russia, focusing especially on his relationship with American businessperson Armand Hammer. He casts this scene against the second Lenin—the hunter on the far end of the country, in Siberia, at the far end of the century, the 1990s, who is tasked with improvising postsocia
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Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis and uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the western world. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, several emerging issues remain debated. Specifically, the genotype–phenotype correlation, the role of advanced imaging techniques and genetic testing, the lack of appropriate risk stratification models, the need for a multiparametric and multidisciplinary approach for device implantation, and a continuous reclassification of the disease during follow-up remain challenging issues in clinical practice. Therefore, the aim of this Special Issue is to shed the light on the most recent advancements in characterization and clinical management of DCM in order to unveil the conundrum of this particular disease.
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Demographische Alterung und technischer Fortschritt sind maßgebliche Ursachen für steigende Ausgaben im Gesundheitswesen. Reaktionen hierauf sind zusehends Beitragssatzsteigerungen und Kostendämpfungsmaßnahmen, weshalb der Markt für Gesundheitsgüter seine Wachstumspotenziale nicht voll auszuschöpfen vermag. In dieser Arbeit werden die positiven Aspekte der Gesundheit für die wirtschaftliche Entwicklung herausgearbeitet. Darüber hinaus wird das Zusammenspiel von Gesundheit und Bildung analysiert, da Bildung die Rolle eines zentralen Wachstumsmotors zukommt. Eine empirische Untersuchung gibt zudem Aufschluss über die wesentlichen Determinanten eines guten Gesundheitsverhaltens sowie einer guten Gesundheit als Voraussetzung für stetiges Wirtschaftswachstum.
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The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. NPs have also been implicated in the pathogenesis of several cardiovascular diseases (CVDs), including hypertension, atherosclerosis, heart failure, and stroke. A fine comprehension of the molecular mechanisms dependent from NPs and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major CVDs. Finally, the opportunity to target NPs in order to develop new therapeutic tools for a better treatment of CVDs has been developed over the years. The current Special Issue of the Journal covers all major aspects of the molecular implications of NPs in physiology and pathology of the cardiovascular system, including NP-based therapeutic approaches.
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