Search results (303,175)

Public

Molecular Pathways of Estrogen Receptor Action

CC BY-NC-ND

ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid ‘non-genomic’ and ‘genomic’ ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, “Molecular Pathways of Estrogen Receptor Action”, promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system.]

PDF document image preview
Public

Tokki Tofu Extra Firme

Guia y recetario

PDF document image preview
Public

www-astropalash-in-.pdf

Astrologer Howrah and Kolkata Palash

Jyotish Sarbogya Palash said Destiny is written in paradise, they say. Yet, is there an approach to modify the awful that might have unfolded upon you? Or on the other hand change how everything is moving? Indeed, there is! With the administrations of Mr. K.P. Tripathi, you can get help without any problem. If you have been confronting serious medical conditions from quite a while, it should be because of the situation of the planets in your horoscope. Besides that he is one of the most popular astrologer in Howrah since last 3 decades. You should counsel us astrologer from Kolkata once to counsel about examination of your issues. Some of the time, the arrangements are straightforward and we essentially increment the issue because of carelessness.

PDF document image preview
Public

Antioxidant Properties of Natural Products: A Themed Issue in Honor of Professor Isabel C.F.R. Ferreira

CC BY

It would be almost impossible to discuss natural products without mentioning the extensive knowledge that Professor Isabel C.F.R. Ferreira has contributed to this field. She has been an instrumental scientist in the development and dissemination of information about these products; throughout her career as a researcher, she explored more than 300 food matrices, including plants and mushrooms, as possible sources of these natural compounds. In her studies, the determination of the bioactive properties of the developed extracts and identified molecules from natural matrices stand out.Antioxidant properties are essential to break the oxidation chain that can occur in an organism, for example, in the human body, or on a substrate, such as in food. In organisms, the oxidative process may be responsible for the generation of free radicals that attack cells, which leads to the development of serious diseases, such as cardiovascular and neurological disorders. The intake of compounds with antioxidant capacities can provide beneficial health effects. In food, oxidation can lead to the loss of product quality due to the deterioration of chemical, physical, and sensory characteristics. Natural products with antioxidant activity can add value to food products due to their functional properties and health benefits.Given the importance of minimizing oxidative processes, several authors have been looking for new compounds with antioxidant activity. In this context, plants, mushrooms, and marine and bee products, among others, may have several classes of compounds in their chemical composition that exert this bioactivity, such as vitamins, polyphenols, organic acids, and pigments. In this Special Issue, Antioxidants Properties of Natural Products: A Themed Issue in Honor of Professor Isabel C.F.R. Ferreira, 23 selected studies explore different food matrices as sources of bioactive molecules with potential use as natural products with several functionalities, including antioxidants properties.

PDF document image preview
Public

Things to Consider When Choosing an Outdoor Dog Fence

Dog Proofer

Dog Proofer informs about things to consider when choosing an outdoor dog fence. For more details, visit: www.dogproofer.com.

PDF document image preview
Public

Real Deal Ecom.pdf

Introducing Real Deal Ecom “Where is an honest course to learn e-commerce from start to finish?” the people asked. Real Deal Ecom is an all-inclusive program covering everything you need to know about shopify dropshipping and facebook ads. No experience or prior skill is necessary – just a goal-hungry nature, an eagerness to learn, and an ability to follow every instruction laid out for you in this guided course are all you’ll ever need to succeed. This is the perfect offer to promote as it has tons of audience potential from low to mid level ecommerce entrepreneurs to complete beginners. This is an easy sell as the niche of dropshipping is growing and people are more interested in starting a online biz or side hustle.

PDF document image preview
Public

Home Remodeling Company | Pappysultimateremodeling.com

Pappy’s Ultimate Remodeling & Construction

We turn your home into the coziest place on Earth. With years of experience and literally thousands of projects completed, the expertise of our team stands apart. We stand behind our promise to deliver quality home remodeling service in a timely manner.

PDF document image preview
Public

1Umsz.pdf

PDF document image preview
Public

Non-Dairy Yogurt Market Analysis Trends and Segments 2018-2026

The global non-dairy yogurt market is expected to be segmented into type, application, and distribution channel.

PDF document image preview
Public

Постановление 353

ЕАС Портал

PDF document image preview
Public

Forse mi conoscevi più degli altri

Dissonetti, 10

PDF document image preview
Public

Trauma, Tumors, Spine, Functional Neurosurgery

CC BY

This book is written for graduate students, researchers, and practitioners who are interested in learning how the knowledge from research can be implemented in clinical competences. The first section is dedicated to deep brain stimulation, a surgical procedure which is the paramount example of how clinical practice can take advantage from fundamental research. The second section gathers four chapters on four different topics and illustrates how significant is the challenge to translate scientific advances into clinical practice because the route from evidence to action is not always obvious. It is hoped that this book will stimulate the interest in the process of translating research into practice for a broader range of neurosurgical topics than the one covered by this book, which could result in a forthcoming more comprehensive publication.

PDF document image preview
Public
Public

Olfaction

CC BY

Our senses shape our reality and allow us to adapt to the everlasting changing environment. From all sensory modalities, olfaction is maybe the most intriguing one, probably because olfactory information influences our daily life without us even noticing. However, we can all relate to the powerful impact that the smell of our favorite food has on us. Likewise, olfactory cues could be determinants for partner selection (because love can be blind but not anosmic), mood regulation and cognition. Furthermore, recent studies link early olfactory dysfunctions to the occurrence of devastating pathologies, such as Alzheimer´s and Parkinson´s. Thus, the study of olfaction, at different levels from genetics to behavior, will pave the way for a better understanding of brain processes and associated disorders.

PDF document image preview
Public

Badania Na Prawo Jazdy.pdf

PC

badania lekarskie na prawo jazdy - Badania lekarskie na prawo jazdy są nieodłącznym elementem procesu zdobywania prawa jazdy.

PDF document image preview
Public

Low Reynolds Number

CC BY

This book reports the latest development and trends in the low Re number aerodynamics, transition from laminar to turbulence, unsteady low Reynolds number flows, experimental studies, numerical transition modelling, control of low Re number flows, and MAV wing aerodynamics. The contributors to each chapter are fluid mechanics and aerodynamics scientists and engineers with strong expertise in their respective fields. As a whole, the studies presented here reveal important new directions toward the realization of applications of MAV and wind turbine blades.

PDF document image preview
Public
Public

Madame de Treymes

Edith Wharton

PD-US

An American in Paris at the turn of the nineteenth century, John Durham pays court to an old flame, Fanny Frisbee, now married to the dissolute Marquis de Malrive. Devoutly Catholic, Fanny's husband is unlikely to grant her a divorce or relinquish custody of their young son, who is heir to the family title. When the Malrive family, urged by Fanny's enigmatic sister-in-law, Madame de Treymes, agrees to a divorce, John must decide whether or not he will pursue a future with the woman he loves, but which forces her to give up her son.

PDF document image preview
Public

Tom Swift and His Airship

Victor Appleton

PD-US

PDF document image preview
Public

Ending violence and other human rights violations based on sexual orientation and gender identity: A joint dialogue of the African Commission on Human and Peoples’ Rights, Inter-American Commission on Human Rights and United Nations

CC BY

About the publicationOver the years, the African, Inter-American and United Nations human rights systems have forged important partnerships on a wide-range of human rights issues and approaches. Grounded in the universality of human rights, the three systems have collaborated through actions ranging from joint statements to joint meetings and country visits, the exchange of information on country situations, individual cases and thematic issues, as well as relying on each other’s case law, decisions and procedural developments.This collaboration has been anchored in frameworks such as the 1993 Vienna Declaration and Programme of Action, the regular dialogue between global and regional human rights mechanisms mandated by the Human Rights Council, the 2009 Memorandum of Understanding between the Organisation of American States and the African Union, the 2012 Addis Ababa Roadmap between the special procedures of the UN Human Rights Council and those of the African Commission on Human and Peoples’ Rights and the 2010 and 2014 Memorandums of Understanding between the Office of the UN High Commissioner for Human Rights and the African Union Commission and Inter- American Commission on Human Rights, respectively.The joint dialogue held on 3 November 2015 in Banjul was firmly located within these frameworks. This timely dialogue enabled each institution to exchange information and experiences, to review approaches, challenges and good practices within each system, and to reaffirm our common resolve to address the serious human rights violations based on sexual orientation and gender identity that take place in all regions.This report and the accompanying background papers capture the content and outcomes of the joint dialogue. We hope that it can provide a basis for further collaboration in future and that States and other stakeholders will find it useful to inform their efforts to combat violence, discrimination and other human rights violations based on sexual orientation and gender identity.Editor: Centre for Human RightsTable of ContentsKey conceptsList of acronymsMessage of supportForewordFinal report: Joint thematic dialogue on sexual orientation and gender identityAnnex 1: List of participantsAnnex 2: Agenda of joint dialogueAnnex 3: Resolution 275Annex 4: Norms, case law and practices of sexual orientation and gender identity in the African human rights systemAnnex 5: Norms, cases and practices relevant to sexual orientation and gender identity in the Inter-American human rights systemAnnex 6: Norms, case law and practices on sexual orientation, gender identity and intersex status in the United Nations systemAnnex 7: HIV, human rights and sexual orientation and gender identity

PDF document image preview
Public

CVJURY -Cover Letters Design

Itech fast

Customize your cv with cvjury and get best cv templates and cover letter designs for you. We are one of the cv maker online experts who provide various facilities and make your cv look professional,unique and lands you to your interviews and dream job.For more information you can visit our website :https://cvjury.com/cv-templates/

PDF document image preview
Public