From the New York Times bestselling author of the Brown Sisters trilogy, comes a laugh-out-loud story about a quirky content creator and a clean-cut athlete testing their abilities to survive the great outdoors--and each other.Bradley Graeme is pretty much perfect. He's a star football player, manages his OCD well (enough), and comes out on top in all his classes . . . except the ones he shares with his ex-best friend, Celine.Celine Bangura is conspiracy-theory-obsessed. Social media followers eat up her takes on everything from UFOs to holiday overconsumption--yet, she's still not cool enough for the popular kids' table. Which is why Brad abandoned her for the in-crowd years ago. (At least, that's how Celine sees it.)These days, there's nothing between them other than petty insults and academic rivalry. So when Celine signs up for a survival course in the woods, she's surprised to find Brad right beside her.Forced to work as a team for the chance to win a grand prize, these two
We combine laser-cut characters with robust, impact-modified acrylic to create our signature 4D number plates.
مایکروسافت لایسنس، نماینده رسمی و تأمینکننده اصلی لایسنسهای قانونی مایکروسافت در ایران است. این مجموعه به عنوان تنها Microsoft Partner رسمی در ایران، با بیش از ده سال سابقه، به ارائه لایسنسهای اورجینال محصولات مایکروسافت میپردازد. با همکاری با بیش از ۲۰۰ سازمان دولتی، خصوصی و بینالمللی، و ارائه خدمات به هزاران مشتری حقیقی و حقوقی، مایکروسافت لایسنس نقش مؤثری در تأمین مطمئن نرمافزارهای قانونی در کشور ایفا میکند.علیرغم محدودیتهای ناشی از تحریمها، این شرکت با تکیه بر شخصیت حقوقی مستقل خود در انگلست
Braze is a customer engagement platform that helps businesses manage and optimize their marketing efforts. They offer various tools and solutions for creating personalized marketing campaigns, tracking user behavior, and improving customer engagement. To become a certified Braze marketer, you would typically need to go through their official certification program.
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Living cells require a constant supply of energy for the orchestration of a variety of biological processes in fluctuating environmental conditions. In heterotrophic organisms, energy mainly derives from the oxidation of carbohydrates and lipids, whose chemical bonds breakdown allows electrons to generate ATP and to provide reducing equivalents needed to restore the antioxidant systems and prevent from damage induced by reactive oxygen and nitric oxide (NO)-derived species (ROS and RNS). Studies of the last two decades have highlighted that cancer cells reprogram the metabolic circuitries in order to sustain their high growth rate, invade other tissues, and escape death. Therefore, this broad metabolic reorganization is mandatory for neoplastic growth, allowing the generation of adequate amounts of ATP and metabolites, as well as the optimization of redox homeostasis in the changeable environmental conditions of the tumor mass. Among these, ROS, as well as NO and RNS, which are produced at high extent in the tumor microenvironment or intracellularly, have been demonstrated acting as positive modulators of cell growth and frequently associated with malignant phenotype. Metabolic changes are also emerging as primary drivers of neoplastic onset and growth, and alterations of mitochondrial metabolism and homeostasis are emerging as pivotal in driving tumorigenesis.Targeting the metabolic rewiring, as well as affecting the balance between production and scavenging of ROS and NO-derived species, which underpin cancer growth, opens the possibility of finding selective and effective anti-neoplastic approaches, and new compounds affecting metabolic and/or redox adaptation of cancer cells are emerging as promising chemotherapeutic tools.In this Research Topic we have elaborated on all these aspects and provided our contribution to this increasingly growing field of research with new results, opinions and general overviews about the extraordinary plasticity of cancer cells to change metabolism and redox homeostasis in order to overcome the adverse conditions and sustain their “individualistic” behavior under a teleonomic viewpoint.
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College graduation is quickly approaching. You will walk across the stage, receive your hard-earned diploma and land your first job. Congratulations! You did it! But before you make any major financial decisions, take some time to make a financial plan, including a budget. Be prepared to tell your money what it is going to do for you instead of the other way around.
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Alexandria Engineering Journal, 61 (2022) 12497-12509. doi:10.1016/j.aej.2022.06.029
Excel in the field of energy efficiency and environmental sustainability with the comprehensive AEE-CEA practice test PDF dumps. Crafted to mirror the content and complexity of the AEE Certified Energy Auditor (CEA) exam, these practice tests offer a diverse range of questions and scenarios to enhance your knowledge and skills in energy auditing, conservation measures, and sustainable practices. Each question is accompanied by detailed explanations, facilitating a deep understanding of critical concepts and methodologies. By harnessing the power of these practice test PDF dumps, you'll cultivate the confidence and expertise needed to thrive in the AEE-CEA exam. Attain your certification as a Certified Energy Auditor and demonstrate your proficiency in advancing energy efficiency and environmental responsibility.
"Non-Tubal Ectopic Pregnancy" is a comprehensive book, written in an organized and concise format. The book offers an immersion into non-tubal ectopic pregnancy and the reader is invited, chapter after chapter, to visit the most important aspects of non-tubal ectopic pregnancies. The book covers all aspects of non-tubal ectopic pregnancies including epidemiology, diagnosis, and management. Experts from all over the world have contributed to it, bringing the best from their research.The book presents the reader with the latest advances on non-tubal ectopic pregnancies.