Corn leaf - a potential functional food Studies suggest that the leaf extract exhibited significant CNS activity and plant leaves contain alkaloids, tannins, mucilage, flavonoids, anthocyanin, leuco-anthocyanin, coumarins, heteroside etc. Mood enhancing effects of the leaf extract containing 6-methoxybenzoxazolinone (6-MBOA) have been noted: in humans, there were statistically significant improvements in mood states and improved sleep quality in clinical study participants. It has been marketed as SerenZea™ or Maizinol - found to induce rate limiting enzymes (tryptophan-5-hydroxylase, and N-acetyltransferase) in the biosynthesis of serotonin/melatonin thus regulating serotonin/melatonin biosynthesis and inhibiting tryptophan dioxygenase. - efficacious in reducing cortisol in human clinical studies - improve overall mental well-being as it was measured by the Profile of Mood States (POMS) in human clinical studies. 1 - supports mood and mental stress in human clinical studies Mental health status using corn leaf extract showed statistically significant improvements in mood state and well-being compared to their baseline (37–58% improvement at 250 mg/day and 36–42% improvement at 500 mg/day) [1, 2, 3] A large aqueous extraction of corn leaf yielded a powder: [1] https://www.liebertpub.com/doi/10.1089/jmf.2021.0197 [2] https://www.mdpi.com/2304-8158/4/2/130 [3] https://unigen.net/ingredients/serenzea/ 2