Spirulina and the Brain Containing high levels of protein and many polyphenols, including chlorophyll a and C- phycocyanin, it has antioxidant, neuroprotective and anti-inflammatory therapeutic effects. Spirulina also appears to protect and enhance cognitive function. Research has shown spirulina enriched diets enhance striatal dopamine recovery and induce rapid changes to 1 microglia activation after injury of the dopamine system. A Spirulina diet can protect against neuroinflammation and decreased antioxidant defence in brain. Promising pre-clinically for neurodegenerative things and MS. In autoimmune CNS conditions, it could potentially improve neuroinflammation, protect from demyelination and axonal loss. It modulated the expression of genes related to remyelination, gliogenesis and axon-glia processes. Included in the diet, it promotes activation of BDNF/CREB neuroprotective signaling pathways in neuronal cells. It increased superoxide dismutase, catalase, and glutathione peroxidase gene expression and decreasing damage from oxidative stress Phycocyanin and related constituents are one interesting component, potently neurorestorative, improving oxidative status, improving neuroinflammation, protecting from demyelination and axonal loss, modulating the expression of genes related to remyelination, gliogenesis and axon-glia processes etc 2 3