1 MATERIAL SAFETY DATA SHEET Section 1 - Product and Company Identification Product Name: Adv anced Clinicals Hyaluronic Acid Gel Crea m Formulation# 6 608SSR 2 Manufacturer Information Concept Laboratories, Inc. 1400 West Wabansia Avenue Chicago, IL 60642 Tel. : (773) 395 - 7300 Fa x: (773) 395 - 7310 In case of emergency: Chem Tel 1(800) 255 - 3924 International +01 - 813 - 248 - 0585 Section 2 - Hazards Identification Appearance: Liquid Classification of the substance or mixture : Not a hazardous substance or mixt ure. GHS Label elem e nts, including precautionary statements : Not a hazardous substance or mixture. Hazards not otherwise classified (HNOC) or not covered by GHS : none HMIS Ratings: Health: 1 Fire: 0 Reactivity: 0 Hazard Scale: 0= Minimal 1= Slight 2= Moderate 3= Se r ious 4= Severe Section 3 - Composition / Information on Ingredients The complete ingredient list for the finished product(s) is as follows: Water (Aqua), Propanediol, Dimethicone, Glycerin, Pyrus Malus (Apple) Fruit Extract, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Hyaluronate, Aloe Barbadensis Leaf Juice, Dipotassium Glycyrrhizate, Butylene Glycol, Caulerpa Lentillifera Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Extract, Cymbopogon Martini Oil, Cyanocobalamin, Hydroxyethylcellulose, Sea Salt, Carrageenan, Vaccinium Angustifolium (Blueberry) Fruit Extract , Ascorbic Acid, Polysorbate 20, Rosa Damascena Flower Extract, Phenoxyethanol, Tocopherol, Maltodextrin, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Geraniol, Linalool. The product(s) does not contain ingredients considered hazardous as defined by OSHA, 29 CFR1910.1200 and/or WHMIS under the HPA. Section 4 - Fi rst Aid Measures Eyes: Immediately thoroughly rinse eyes with water for at least 15 minutes is recommended. If discomfort or irritation persists, contact a physician. Skin Problem: Discontinu e use of product. Apply cold compresses to af fected areas to rel ieve any discomfort. If discomfort persists, contact a physician. Ingestion: Consult a Physician. Inhalation: Remove victim to fresh air if breathing is difficult. Get immediate medical assi stance. 2 Section 5 - Fire and Explosion Hazard Data Flammable Sta tus: Non - flammable Flash Point: N/A Flammable Limits (% by volume): LEL: Not determined UEL: Not determined. Hazardous Combustion Products: Incomplete burning can produce carbon monoxide and/ or carbon dioxide and other toxic gases. Exti nguishing Media: Us e chemical foam, dry chemical, carbon dioxide or water. Firefighting Equipment: Wear positive pressure self - contained breathing apparatus. NFPA Ratings: Health: 1 Fire: 0 Reactivity: 0 Hazar d Scale: 0= Minimal 1= Slight 2= Moderate 3= Serious 4= Sev ere Section 6: Accidental Release Measures Small Spill and Leak: Absorb liquid and scrub the area with detergent. Dilute with water. Large Spill and Leak: Use safety glasses or safety goggles if splash hazards exist; use gloves and other protective clothin g (apron, boots, etc.) to prevent skin contact. Section 7: Handling and Storage Handling: No unusual handling or storage requirements. Storage: Storage in large quantities (as in warehouses) should be in a well - ventilated, cool area. K eep out of reach of children. Section 8: Exposure Control/Personal Protection For Household Settings: This is a personal care or cosmetic product that is safe for consumers and other users under normal and reaso nably foreseen use. Exposure Limits: Not Avai lable. Engineering Controls: Use adequate ventilation. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or safety goggles if splash hazards exist. Skin: Use gloves and other protective clothing (apron, boots, etc) to prevent prolo nged skin contact. Clothing: Wear appropriate protective clothing to prevent prolonged skin exposure. Respirator: When required, use an approved air - purifying respirator. Section 9: Physical and Chemical Prope rties Physical State: Liquid Flash Point: N /A Color: White - Off white Vapor Press./Density: N/A Odor: Floral Solubility in water: Dispersible pH: 5.0 - 7 .0 Specific Gravity/Density: 0.9 - 1.1 Section 10: Stability and Reactivity Chemical Stability: No applicable information has been found. Con ditions to avoid: N one. Incompatibilities: None Hazardous Polymerization: Will not occur. Hazardous Decomposition Products: None identified. Section 11: Toxicology Information This is a personal care or cosmeti c product that is safe for consumers and othe r users under inten ded and reasonably foreseeable use. Acute Toxicity: Finished product is not expected to have chronic health effects. 3 Chronic Effects: Finished product is not expected to have chronic health ef fects. Target Organs: No adverse health effec ts on target organs expected for finished product. Carcinogenicity: Finished product is not expected to be carcinogenic. NTP: No IARC: No OSHA: No Section 12: Ecological Information Environmental Data: The prod uct ingredients are expected to be safe for t he environment at c oncentrations predicted under normal use and accidental spill scenarios. Section 13: Disposal Considerations Disposal should be in accordance with Federal, State/Provincial and Local Environme ntal Control regulations. For Household Setti ngs: The following instructions are for consumer usage only. Do not discharge product into natural waters without pre - treatment or adequate dilution. For Non - Household Settings: Products covered by this MSDS, in their original form, when disposed as waste, are considered non hazardous waste according to Federal RCRA regulations (40 CFR 261). Disposal should be in accordance with local, state and federal regulations. California Waste Code: 331 Section 14: Transpor t Information Finished packaged product trans ported by ground (D OT): Not Regulated Finished packaged product transported by vessel (IMDG): Not Regulated Finished packaged product transported by air (IATA): Not Regulated Not a USDOT or Canadian TDG regulat ed product. Section 15: Regulatory Informatio n All ingredients o f this product are listed or are excluded from listing under the U.S. Toxic Substances Control Act (TSCA) Inventory List. EU DPD (Dangerous Products Directive) Classification (DPD 88/379/EEC) Regulated as a Cosmetic and/or Drug under F DA (US), HPB (Canad a), Cosmetic Directive (EU), MHW (Japan) and MOH (China). While the finished product(s) is not considered hazardous as defined in 29 CFR 1910.1200 (d), this MSDS contains valuable information critical to the safe handling and proper use of the product. U S Federal: The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safe to use as per directions on container, box or accom panying literature (where applicable). CERCL A reportable quanti ty (RQ): None. SARA 313/302/304/311/312 chemicals: Ingredient CAS # Level 313 302 304 311 312 Phenoxyethanol 122 - 99 - 6 0.1 - 1.0% Yes No No No No 4 Canada: All ingredients are CEPA app roved for import to Canada. This product has been classified in accordance with the hazard criteria of the Canadian Controlled Products Regulations (CPR) and this MSDS contains all information required by the CPR. US States CA Prop 65: This product is not subject to warning labeling under California Proposition 65. St ate Right - to - Know: The following ingredients are present in the finished product and are listed on the following state right - to - know lists: Ingredient CAS # Level State Glycerin 56 - 8 1 - 5 1 .0 - 10.0 % IL MA PA RI Butylene Glycol 1 07 - 88 - 0 1.0 - 10.0 % NJ PA Hexylene Glycol 107 - 41 - 5 0.1 - 1 .0 % IL MA NJ PA RI Phenoxyethanol 122 - 99 - 6 0.1 - 1.0% IL NJ PA Citric acid 77 - 92 - 9 0.001 - 0.1 % NJ PA Sodium H ydroxide 1310 - 73 - 2 0.1 - 1 .0 % CA IL FL LA MA MN NJ NY PA RI Linalool 78 - 70 - 6 0.01 - 0.0001 % MA NJ PA Section 16: Other Information All inf ormation provided herein is based upon data obtained from the raw material manufacturer and/or recognized technical sources. While the information above is believed to be true and accurate Concept Laboratories, Inc. makes no representati ons as to its accur acy or sufficiency. It is intended solely to assist in evaluating the suitability and proper use of this product and in implementing safety precautions and procedures. Final determination of suitability of any material is the sole respon sibility of the use r. This information applies only to the product designated above and does not necessarily apply to its use in combination with other materials, products, chemical comp ounds, structures or processes. Issued: October 19, 2022