In the world of molecular biology, the success of downstream applications—such as Next-Generation Sequencing (NGS), cloning, and Sanger sequencing—hinges entirely on the purity of the initial DNA sample. After a PCR cycle, the reaction mixture is often cluttered with leftover primers, dNTPs, enzymes, and salts. To remove these contaminants without losing precious genetic material, researchers are increasingly turning to magnetic beads as the gold standard for precision purification.