The most common cause of QuickBooks Payroll Update Error 15222 is a problem with the digital signature verification procedure that occurs during a payroll update. This error can be a sign that something is amiss with the Internet Explorer configuration, or that the update process is being blocked by an antivirus or firewall. Making sure the Internet Explorer settings are accurate, updating the antivirus and firewall settings, and downloading the payroll update again are the steps involved in fixing this problem. Error 15222 must be fixed in order to ensure timely payroll processing and compliance. For additional help & explanation, you need to dial 1.855.856.0042 to connect with our QB Professionals Team.