2020_Claymation Project_Virtual.pdf - ef

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Action Potential & Nervous Disorders Claymation A Claymation is one of many forms of stop-motion animation. Each animated piece, either character or background, is "deformable"—made of a malleable substance, usually clay. (citation – Wikipedia) Project Goal: Create a unique Claymation to show the process of action potentials (part 1) and synapse (part 2) through a neuron. Research a specific disease/disorder or drug and its effects on the nervous system then demonstrate through Claymation (part 3) how the disease/disorder or drug changes the action potential and/or synapse to disrupt homeostasis. When I grade the project, I am grading the ACTION/MOTION of the Claymation, not words or other textual information added to the Claymation. This is a Claymation movie I watch, not a movie with subtitles or a book I read. Part 1. Demonstrate the events of Resting Potential, Depolarization, Repolarization, Hyperpolarization. Remember to include the following for EACH event: a. Action of Sodium and potassium channels b. Action of Sodium potassium pump c. Electrical charge inside relative to outside d. Concentration gradient of sodium e. Concentration gradient of potassium f. Movement of ions Part 2. The Synapse – Demonstrate the events of a signal transduction pathway that occurs once the action potential reaches the synaptic knob, the synapse and onto the cell membrane of the post-synaptic neuron, triggering an action potential in the post-synaptic neuron. a. Calcium ions – as a second messenger b. Vesicles c. Neurotransmitters d. Exocytosis e. Movement of neurotransmitters f. Synaptic knob – synaptic cleft g. Receptor proteins Part 3. Specific Disease, Disorder or Drug – sign up on itslearning registration page. a. Name the neurological disorder or drug. b. Demonstrate the cellular communication problem that exists due to the disorder or drug you specifically selected for the project. c. Demonstrate how homeostasis is disrupted due to the disorder or drug you specifically selected for the project. d. Demonstrate the effects of a disruption in homeostasis caused by the disorder or drug you specifically selected for the project. The Synapse Concentration Gradient Across a Membrane Creating Membrane Potential